Therapeutic Potential of Aptamer–Protein Interactions
AS Shraim, BA Abdel Majeed… - ACS Pharmacology & …, 2022 - ACS Publications
Aptamers are single-stranded oligonucleotides (RNA or DNA) with a typical length between
25 and 100 nucleotides which fold into three-dimensional structures capable of binding to …
25 and 100 nucleotides which fold into three-dimensional structures capable of binding to …
DNA-based nanomaterials as drug delivery platforms for increasing the effect of drugs in tumors
AN Shishparenok, VV Furman, DD Zhdanov - Cancers, 2023 - mdpi.com
Simple Summary The use of drugs based on nucleic acids is a promising direction in
antitumor therapy. Some modified oligonucleotide analogs, such as antisense …
antitumor therapy. Some modified oligonucleotide analogs, such as antisense …
Hitting the diagnostic sweet spot: Point-of-care SARS-CoV-2 salivary antigen testing with an off-the-shelf glucometer
Significant barriers to the diagnosis of latent and acute SARS-CoV-2 infection continue to
hamper population-based screening efforts required to contain the COVID-19 pandemic in …
hamper population-based screening efforts required to contain the COVID-19 pandemic in …
KIT mutations and expression: current knowledge and new insights for overcoming IM resistance in GIST
S Zhou, O Abdihamid, F Tan, H Zhou, H Liu, Z Li… - Cell Communication and …, 2024 - Springer
Gastrointestinal stromal tumor (GIST) is the most common sarcoma located in
gastrointestinal tract and derived from the interstitial cell of Cajal (ICC) lineage. Both ICC …
gastrointestinal tract and derived from the interstitial cell of Cajal (ICC) lineage. Both ICC …
Enhanced Electrochemical Biosensing of the Sp17 Cancer Biomarker in Serum Samples via Engineered Two-Dimensional MoS2 Nanosheets on the Reduced …
In the present investigation, we reported a label-free and highly effective immunosensor for
the first time employing a nanostructured molybdenum disulfide nanosheets@ reduced …
the first time employing a nanostructured molybdenum disulfide nanosheets@ reduced …
Anti-KIT DNA aptamer-conjugated porous silicon nanoparticles for the targeted detection of gastrointestinal stromal tumors
Evaluation of Gastrointestinal Stromal Tumors (GIST) during initial clinical staging, surgical
intervention, and postoperative management can be challenging. Current imaging …
intervention, and postoperative management can be challenging. Current imaging …
Development of a soluble KIT electrochemical aptasensor for cancer theranostics
An electrochemical sensor based on a conformation-changing aptamer is reported to detect
soluble KIT, a cancer biomarker, in human serum. The sensor was fabricated with a …
soluble KIT, a cancer biomarker, in human serum. The sensor was fabricated with a …
Aptamer-based technology for gastric cancer theranostics
QY Lv, HF Cui, X Song - Analytical Methods, 2023 - pubs.rsc.org
Gastric cancer is one of the most common causes of cancer death worldwide. This cancer
exhibits high molecular and phenotype heterogeneity. The overall survival rate for gastric …
exhibits high molecular and phenotype heterogeneity. The overall survival rate for gastric …
IgA autoantibodies target pulmonary surfactant in patients with severe COVID-19
Complications affecting the lung are hallmarks of severe coronavirus disease 2019 (COVID-
19). While there is evidence for autoimmunity in severe COVID-19, the exact mechanisms …
19). While there is evidence for autoimmunity in severe COVID-19, the exact mechanisms …
Nucleic acid covalent tags
M Su, T Peng, Y Zhu, J Li - ChemBioChem - Wiley Online Library
The selective and site‐specific chemical labeling of proteins has emerged as a pivotal
research area in chemical biology and cell biology. An effective protein labeling typically …
research area in chemical biology and cell biology. An effective protein labeling typically …