[HTML][HTML] Neoadjuvant rectal (NAR) score: a new surrogate endpoint in rectal cancer clinical trials

TJ George, CJ Allegra, G Yothers - Current colorectal cancer reports, 2015 - Springer
The conduct of clinical trials in colorectal cancer has historically relied upon endpoints such
as disease-free (DFS) or overall survival (OS). While ideal, these endpoints require long …

Surgery for colorectal cancer in elderly patients: a systematic review

PD Simmonds, L Best, S George, C Baughan… - The Lancet, 2000 - thelancet.com
Background The effectiveness of surgery for colorectal cancer depends on it being carried
out safely, which allows most patients to return to productive lives, with an improved …

Guidelines 2000 for colon and rectal cancer surgery

H Nelson, N Petrelli, A Carlin, J Couture… - Journal of the …, 2001 - academic.oup.com
Background: Oncologic resection techniques affect outcome for colon cancer and rectal
cancer, but standardized guidelines have not been adopted. The National Cancer Institute …

Impact of the introduction and training of total mesorectal excision on recurrence and survival in rectal cancer in The Netherlands

E Kapiteijn, H Putter… - British journal of …, 2002 - Wiley Online Library
Background: Local control and survival following surgical treatment of rectal cancer have
been improved by the introduction of total mesorectal excision (TME). The aim of this study …

Hospital and surgeon procedure volume as predictors of outcome following rectal cancer resection

D Schrag, KS Panageas, E Riedel, LD Cramer… - Annals of …, 2002 - journals.lww.com
Hospital and Surgeon Procedure Volume as Predictors of Outco... : Annals of Surgery Hospital
and Surgeon Procedure Volume as Predictors of Outcome Following Rectal Cancer Resection …

Practice parameters for the management of rectal cancer (revised)

JJ Tjandra, JW Kilkenny, WD Buie… - Diseases of the Colon …, 2005 - journals.lww.com
The American Society of Colon and Rectal Surgeons is dedicated to assuring high-quality
patient care by advancing the science, prevention, and management of disorders and …

Impact of surgical and pathologic variables in rectal cancer: a United States community and cooperative group report

L Stocchi, H Nelson, DJ Sargent… - Journal of Clinical …, 2001 - ascopubs.org
PURPOSE: Substantial and successful effort has been focused on decreasing the risk of
local failure after rectal cancer surgery through the use of adjuvant therapies. Our study …

Relation of hospital volume to colostomy rates and survival for patients with rectal cancer

DC Hodgson, W Zhang, AM Zaslavsky… - Journal of the …, 2003 - academic.oup.com
Background: Postoperative mortality after some types of cancer surgery is inversely related
to the number of operations performed at a hospital (ie, hospital volume). This study …

Phase III trial of fluorouracil-based chemotherapy regimens plus radiotherapy in postoperative adjuvant rectal cancer: GI INT 0144

SR Smalley, JK Benedetti, SK Williamson… - Journal of clinical …, 2006 - ascopubs.org
Purpose Adjuvant chemoradiotherapy after or before resection of high-risk rectal cancer
improves overall survival (OS) and pelvic control. We studied three postoperative …

Training and quality assurance for rectal cancer: 20 years of data is enough

P Quirke - The lancet oncology, 2003 - thelancet.com
Rectal cancer is a common disease with a high rate of mortality. During the past 20 years,
substantial improvements have been made in the surgical, pathological, radiological, and …