mRNA vaccines: The dawn of a new era of cancer immunotherapy
Z Deng, Y Tian, J Song, G An, P Yang - Frontiers in Immunology, 2022 - frontiersin.org
mRNA therapy is a novel anticancer strategy based on in vitro transcription (IVT), which has
potential for the treatment of malignant tumors. The outbreak of the COVID-19 pandemic in …
potential for the treatment of malignant tumors. The outbreak of the COVID-19 pandemic in …
Clinical and immunological effects of mRNA vaccines in malignant diseases
In vitro-transcribed messenger RNA-based therapeutics represent a relatively novel and
highly efficient class of drugs. Several recently published studies emphasize the potential …
highly efficient class of drugs. Several recently published studies emphasize the potential …
Chemical modifications of mRNA ends for therapeutic applications
M Warminski, A Mamot, A Depaix… - Accounts of Chemical …, 2023 - ACS Publications
Conspectus Messenger ribonucleic acid (mRNA) is the universal cellular instruction for
ribosomes to produce proteins. Proteins are responsible for most of the functions of living …
ribosomes to produce proteins. Proteins are responsible for most of the functions of living …
Advances in mRNA therapeutics for cancer immunotherapy: from modification to delivery
RNA vaccines have demonstrated their ability to solve the issues posed by the COVID-19
pandemic. This success has led to the renaissance of research into mRNA and their …
pandemic. This success has led to the renaissance of research into mRNA and their …
Messenger RNA vaccines for cancer immunotherapy: progress promotes promise
AL Huff, EM Jaffee, N Zaidi - The Journal of Clinical …, 2022 - Am Soc Clin Investig
The COVID-19 pandemic has elevated mRNA vaccines to global recognition due to their
unprecedented success rate in protecting against a deadly virus. This international success …
unprecedented success rate in protecting against a deadly virus. This international success …
[HTML][HTML] The paradigm shift in treatment from Covid-19 to oncology with mRNA vaccines
J Wei, AM Hui - Cancer Treatment Reviews, 2022 - Elsevier
Abstract mRNA vaccines have gained popularity over the last decade as a versatile tool for
developing novel therapeutics. The recent success of coronavirus disease (COVID-19) …
developing novel therapeutics. The recent success of coronavirus disease (COVID-19) …
The pivotal role of chemical modifications in mRNA therapeutics
After over a decade of development, mRNA has recently matured into a potent modality for
therapeutics. The advantages of mRNA therapeutics, including their rapid development and …
therapeutics. The advantages of mRNA therapeutics, including their rapid development and …
mRNA therapeutic modalities design, formulation and manufacturing under pharma 4.0 principles
In the quest for a formidable weapon against the SARS-CoV-2 pandemic, mRNA
therapeutics have stolen the spotlight. mRNA vaccines are a prime example of the benefits …
therapeutics have stolen the spotlight. mRNA vaccines are a prime example of the benefits …
Advances in Nonviral mRNA Delivery Materials and Their Application as Vaccines for Melanoma Therapy
Messenger RNA (mRNA) vaccines are promising platforms for cancer immunotherapy
because of their potential to encode for a variety of tumor antigens, high tolerability, and …
because of their potential to encode for a variety of tumor antigens, high tolerability, and …
Cytidine-containing tails robustly enhance and prolong protein production of synthetic mRNA in cell and in vivo
Synthetic mRNAs are rising rapidly as alternative therapeutic agents for delivery of proteins.
However, the practical use of synthetic mRNAs has been restricted by their low cellular …
However, the practical use of synthetic mRNAs has been restricted by their low cellular …