Peripheral neuropathies are characterized by nerves damage and axonal loss, and they
could be classified in hereditary or acquired forms. Acquired peripheral neuropathies are …

Background Despite the increasing knowledge of the etiology of neuropathic pain, this type
of chronic pain is resistant to available analgesics in approximately 50% of patients and …

Vincristine (VCR), an alkaloid extracted from vinca, is often used in combination with other
chemotherapeutic drugs to treat a variety of cancers, such as acute lymphoblastic leukaemia …

Brain cancer and leukemia are the most common cancers diagnosed in the pediatric
population and are often treated with lifesaving chemotherapy. However, chemotherapy …

Disclosures: K. Schroder reported" other" from Inflazome Ltd outside the submitted work; in
addition, K. Schroder had a patent to PCT/EP2017/053498 licensed (Inflazome Ltd), a patent …

Simple Summary The survival rate for pediatric cancers has improved significantly over the
last decades. Conventional chemotherapies play a vital role in pediatric cancer treatment …

The peripheral nervous system comprises an infinity of neural networks that act in the
communication between the central nervous system and the most diverse tissues of the …

Around 20% of the American population have chronic pain and estimates in other Western
countries report similar numbers. This represents a major challenge for global health care …

Vincristine, oxaliplatin, and cisplatin are commonly prescribed chemotherapeutic agents for
the treatment of many tumors. However, a main side effect is chemotherapy-induced …

The high prevalence of pain and the at times low efficacy of current treatments represent a
significant challenge to healthcare systems worldwide. Effective treatment strategies require …