For many decades, sleep researchers have sought to determine which species 'have'rapid
eye movement (REM) sleep. In doing so, they relied predominantly on a template derived …

Recent development of innovative tools for live imaging of actin filaments (F-actin) enabled
the detection of surprising nuclear structures responding to various stimuli, challenging …

Sleep quality declines with age; however, the underlying mechanisms remain elusive. We
found that hyperexcitable hypocretin/orexin (Hcrt/OX) neurons drive sleep fragmentation …

The view that sleep is essential for survival is supported by the ubiquity of this behavior, the
apparent existence of sleep-like states in the earliest animals, and the fact that severe sleep …

Sleep is thought to be restorative to brain energy homeostasis, but it is not clear how this is
achieved. We show here that Drosophila glia exhibit a daily cycle of glial mitochondrial …

The characteristics of the sleep drivers and the mechanisms through which sleep relieves
the cellular homeostatic pressure are unclear. In flies, zebrafish, mice, and humans, DNA …

Por que os grandes gurus do Vale do Silício proíbem seus filhos de usar telas? Você sabia
que nunca na história da humanidade houve um declínio tão acentuado nas habilidades …

In mice and humans, sleep quantity is governed by genetic factors and exhibits age-
dependent variation,–. However, the core molecular pathways and effector mechanisms that …

Microplastics (MPs) are ubiquitous anthropogenic contaminants, and their abundance in the
entire ecosystem raises the question of how far is the impact of these MPs on the biota …

The evolutionary origins of sleep and its sub-states, rapid eye movement (REM) and non-
REM (NREM) sleep, found in mammals and birds, remain a mystery. Although the discovery …