Progressive multifocal leukoencephalopathy (PML) is a rare, devastating demyelinating
disease of the CNS caused by the JC virus (JCV) that occurs in patients with compromised …

Dimethyl fumarate (DMF), a fumaric acid with antioxidant and immunomodulatory properties,
is among the most commonly used oral therapies for relapsing multiple sclerosis (MS) …

Progressive multifocal encephalopathy (PML) is a severe demyelinating disease of the
central nervous system (CNS) caused by JC virus (JCV), which occurs in …

Multiple sclerosis (MS) is a T cell driven autoimmune disease of the central nervous system
(CNS). Despite its association with Epstein-Barr Virus (EBV), how viral infections promote …

JC polyomavirus (JCPyV) is the causative agent of a fatal central nervous system
demyelinating disease known as progressive multifocal leukoencephalopathy (PML). PML …

Progressive multifocal leukoencephalopathy (PML) is a subacute CNS inflammatory disease
seen primarily among immunocompromised patients. It is caused by the JC virus (JCV), a …

The increased use of newer potent immunomodulatory therapies for multiple sclerosis (MS),
including natalizumab, fingolimod, and dimethyl fumarate, has expanded the patient …

Importance Infection with JC virus (JCV) may lead to development of demyelinating
progressive multifocal leukoencephalopathy in patients with multiple sclerosis (MS) who are …

Although CD8 T cells are key players in neuroinflammation, little is known about their
trafficking cues into the central nervous system (CNS). We used a murine model of CNS …

JC Viremia in Natalizumab-Treated Patients with Multiple Sclerosis | New England Journal of
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