Alternative splicing of eukaryotic transcripts is a mechanism that enables cells to generate
vast protein diversity from a limited number of genes. The mechanisms and outcomes of …

Synapses are specialized junctions between neurons in brain that transmit and compute
information, thereby connecting neurons into millions of overlapping and interdigitated …

INTRODUCTION Cells and tissues are made up of diverse molecular building blocks,
organized with nanoscale precision over extended length scales. Newly developed …

The function of neuronal circuits relies on the properties of individual neuronal cells and
their synapses. We propose that a substantial degree of synapse formation and function is …

Cortical interneurons display striking differences in shape, physiology, and other attributes,
challenging us to appropriately classify them. We previously suggested that interneuron …

Synapse organizing proteins are multifaceted molecules that coordinate the complex
processes of brain development and plasticity at the level of individual synapses. Their …

Synapses are fundamental units of communication in the brain. The prototypical synapse-
organizing complex neurexin-neuroligin mediates synapse development and function and is …

Nervous system function relies on complex assemblies of distinct neuronal cell types that
have unique anatomical and functional properties instructed by molecular programs …

Highlights•Proper connectivity of neuronal circuits require the function of glial
cells.•Astrocytes and microglia control synapse formation, elimination and …

Posttranscriptional mechanisms provide powerful means to expand the coding power of
genomes. In nervous systems, alternative splicing has emerged as a fundamental …