Photodynamic and photothermal therapies: synergy opportunities for nanomedicine
Tumoricidal photodynamic (PDT) and photothermal (PTT) therapies harness light to
eliminate cancer cells with spatiotemporal precision by either generating reactive oxygen …
eliminate cancer cells with spatiotemporal precision by either generating reactive oxygen …
[HTML][HTML] Nanocarriers for pancreatic cancer imaging, treatments, and immunotherapies
Pancreatic tumors are highly desmoplastic and immunosuppressive. Delivery and
distribution of drugs within pancreatic tumors are compromised due to intrinsic physical and …
distribution of drugs within pancreatic tumors are compromised due to intrinsic physical and …
In Situ Transforming RNA Nanovaccines from Polyethylenimine Functionalized Graphene Oxide Hydrogel for Durable Cancer Immunotherapy
Messenger RNA (mRNA) vaccine is a promising candidate in cancer immunotherapy as it
can encode tumor-associated antigens with an excellent safety profile. Unfortunately, the …
can encode tumor-associated antigens with an excellent safety profile. Unfortunately, the …
[HTML][HTML] The phospholipid research center: current research in phospholipids and their use in drug delivery
S Drescher, P van Hoogevest - Pharmaceutics, 2020 - mdpi.com
This review summarizes the research on phospholipids and their use for drug delivery
related to the Phospholipid Research Center Heidelberg (PRC). The focus is on projects that …
related to the Phospholipid Research Center Heidelberg (PRC). The focus is on projects that …
[HTML][HTML] Photosensitizer nanoparticles boost photodynamic therapy for pancreatic cancer treatment
Patients with pancreatic cancer (PCa) have a poor prognosis apart from the few suitable for
surgery. Photodynamic therapy (PDT) is a minimally invasive treatment modality whose …
surgery. Photodynamic therapy (PDT) is a minimally invasive treatment modality whose …
Dynamic nanoassemblies of nanomaterials for cancer photomedicine
Photomedicine has long been used for treating cancerous diseases. With advances in
chemical and material sciences, various types of light-activated photosensitizers (PSs) have …
chemical and material sciences, various types of light-activated photosensitizers (PSs) have …
Tailored chemodynamic nanomedicine improves pancreatic cancer treatment via controllable damaging neoplastic cells and reprogramming tumor microenvironment
Y Chen, Y Huang, S Zhou, M Sun, L Chen, J Wang… - Nano Letters, 2020 - ACS Publications
Pancreatic ductal adenocarcinoma (PDAC) strongly resists standard therapies since KRAS-
mutated cancer cells harbor endogenous resistance toward chemotherapy-induced …
mutated cancer cells harbor endogenous resistance toward chemotherapy-induced …
[HTML][HTML] EGFR-targeted photodynamic therapy
L Ulfo, PE Costantini, M Di Giosia, A Danielli… - Pharmaceutics, 2022 - mdpi.com
The epidermal growth factor receptor (EGFR) plays a pivotal role in the proliferation and
metastatization of cancer cells. Aberrancies in the expression and activation of EGFR are …
metastatization of cancer cells. Aberrancies in the expression and activation of EGFR are …
Photodynamic therapy, priming and optical imaging: Potential co-conspirators in treatment design and optimization—a Thomas Dougherty Award for Excellence in …
Photodynamic therapy is a photochemistry-based approach, approved for the treatment of
several malignant and non-malignant pathologies. It relies on the use of a non-toxic, light …
several malignant and non-malignant pathologies. It relies on the use of a non-toxic, light …
Advanced 3D imaging and organoid bioprinting for biomedical research and therapeutic applications
Organoid cultures offer a valuable platform for studying organ-level biology, allowing for a
closer mimicry of human physiology compared to traditional two-dimensional cell culture …
closer mimicry of human physiology compared to traditional two-dimensional cell culture …