Background Although in all sexually reproducing organisms an individual has a mother and
a father, non-genetic inheritance has been predominantly studied in mothers. Paternal …

Drug addiction is a chronic relapsing disorder that makes it a global problem. Genetics and
environmental factors are the two most important factors that make someone vulnerable to …

Rationale Parental drug use around or before conception can have adverse consequences
for offspring. Historically, this research has focused on the effects of maternal substance use …

Paternal cocaine use causes phenotypic alterations in offspring behavior and associated
neural processing. In rodents, changes in first generation (F1) offspring include drug reward …

It is well established that the damaging effects of drugs of abuse, such as cocaine, can
extend beyond the user to their offspring. While most preclinical models of the generational …

Purpose Study of the relationship between prenatal cocaine exposure (PCE) and executive
function (EF) has yielded inconsistent results. The purpose of the current study is to examine …

Background Men of reproductive age increasingly use recreational drugs. While many of
these substances may reduce the quantity and quality of sperm, less is known about the …

Parental exposure to drugs of abuse induces changes in the germline that can be
transmitted across subsequent generations, resulting in enduring effects on gene …

Psychoactive drugs are a popular way to induce pleasant feelings, but also to modify
wakefulness and sleep. In turn, insomnia and circadian often impact on drug-taking …

Evidence suggests that cocaine abuse by mothers results in measurable alterations in the
behavior and neurobiology of first generation (F1) offspring. What is less understood are the …