The need to consider return to work as a main outcome in patients undergoing surgery for diffuse low-grade glioma: a systematic review
JSG Pascual, H Duffau - Acta neurochirurgica, 2022 - Springer
Objective For a long time, return to work (RTW) has been neglected in patients harboring a
diffuse low-grade glioma (LGG). However, a majority of LGG patients worked at time of …
diffuse low-grade glioma (LGG). However, a majority of LGG patients worked at time of …
Brain connectomics applied to oncological neuroscience: from a traditional surgical strategy focusing on glioma topography to a meta-network approach
H Duffau - Acta Neurochirurgica, 2021 - Springer
The classical way for surgical selection and planning in cerebral glioma mainly focused on
tumor topography. The emerging science of connectomics, which aims of mapping brain …
tumor topography. The emerging science of connectomics, which aims of mapping brain …
Constant multi-tasking with time constraint to preserve across-network dynamics throughout awake surgery for low-grade glioma: a necessary step to enable patients …
H Duffau, S Ng, AL Lemaitre, S Moritz-Gasser… - Frontiers in …, 2022 - frontiersin.org
Awake surgery for brain gliomas improves resection while minimizing morbidity. Although
intraoperative mapping was originally used to preserve motor and language functions, the …
intraoperative mapping was originally used to preserve motor and language functions, the …
Beyond avoiding hemiplegia after glioma surgery: the need to map complex movement in awake patient to preserve conation
F Rech, H Duffau - Cancers, 2023 - mdpi.com
Simple Summary Glioma surgery relies on the ability to perform a large extent of resection
while preserving the patient's quality of life, especially regarding complex movement. Our …
while preserving the patient's quality of life, especially regarding complex movement. Our …
The concept of «peritumoral zone» in diffuse low-grade gliomas: oncological and functional implications for a connectome-guided therapeutic attitude
M Silva, C Vivancos, H Duffau - Brain Sciences, 2022 - mdpi.com
Diffuse low-grade gliomas (DLGGs) are heterogeneous and poorly circumscribed
neoplasms with isolated tumor cells that extend beyond the margins of the lesion depicted …
neoplasms with isolated tumor cells that extend beyond the margins of the lesion depicted …
[HTML][HTML] Introducing the concept of brain metaplasticity in glioma: how to reorient the pattern of neural reconfiguration to optimize the therapeutic strategy
H Duffau - Journal of Neurosurgery, 2021 - thejns.org
G liomas, which represent about half of all primary cerebral tumors, generate functional
disturbances by progressing within the brain, with patient survival time still short even with …
disturbances by progressing within the brain, with patient survival time still short even with …
The death of localizationism: The concepts of functional connectome and neuroplasticity deciphered by awake mapping, and their implications for best care of brain …
H Duffau - Revue Neurologique, 2021 - Elsevier
Although clinical neurology was mainly erected on the dogma of localizationism, numerous
reports have described functional recovery after lesions involving presumed non …
reports have described functional recovery after lesions involving presumed non …
Spheresomes are the main extracellular vesicles in low-grade gliomas
M Baselga, P Iruzubieta, T Castiella, M Monzón… - Scientific Reports, 2023 - nature.com
Cancer progression and its impact on treatment response and prognosis is deeply regulated
by tumour microenvironment (TME). Cancer cells are in constant communication and …
by tumour microenvironment (TME). Cancer cells are in constant communication and …
Surgical, functional, and oncological considerations regarding awake resection for giant diffuse lower-grade glioma of more than 100 cm3
S Sauvageot, J Boetto, H Duffau - Journal of Neurosurgery, 2023 - thejns.org
OBJECTIVE Surgery for giant diffuse lower-grade gliomas (LGGs) is challenging, and very
few data have been reported on this topic in the literature. In this article, the authors …
few data have been reported on this topic in the literature. In this article, the authors …
Dynamic interplay between lower-grade glioma instability and brain metaplasticity: proposal of an original model to guide the therapeutic strategy
H Duffau - Cancers, 2021 - mdpi.com
Simple Summary The behavior of diffuse lower-grade glioma (LGG) is changing over time,
spontaneously, and in reaction to therapies. Due to genomic instability and clonal …
spontaneously, and in reaction to therapies. Due to genomic instability and clonal …