[HTML][HTML] Towards understandings of serine/arginine-rich splicing factors

D Li, W Yu, M Lai - Acta Pharmaceutica Sinica B, 2023 - Elsevier
Serine/arginine-rich splicing factors (SRSFs) refer to twelve RNA-binding proteins which
regulate splice site recognition and spliceosome assembly during precursor messenger …

Serine and arginine rich splicing factor 1: a potential target for neuroprotection and other diseases

AM Sandoval-Castellanos, A Bhargava… - Neural regeneration …, 2023 - journals.lww.com
Alternative splicing is the process of producing variably spliced mRNAs by choosing distinct
combinations of splice sites within a messenger RNA precursor. This splicing enables …

HIV-1 Vpr induces ciTRAN to prevent transcriptional repression of the provirus

V Bhardwaj, A Singh, A Choudhary, R Dalavi… - Science …, 2023 - science.org
The functional consequences of circular RNA (circRNA) expression on HIV-1 replication are
largely unknown. Using a customized protocol involving direct RNA nanopore sequencing …

SRSF1 regulates exosome microRNA enrichment in human cancer cells

YF Xu, X Xu, A Gin, JD Nshimiyimana… - Cell Communication and …, 2020 - Springer
Background Exosomes are extracellular vesicles containing a variety of biological
molecules including microRNAs (miRNAs). We have recently demonstrated that certain …

[HTML][HTML] c-MYC regulates mRNA translation efficiency and start-site selection in lymphoma

K Singh, J Lin, Y Zhong, A Burčul, P Mohan… - Journal of Experimental …, 2019 - rupress.org
The oncogenic c-MYC (MYC) transcription factor has broad effects on gene expression and
cell behavior. We show that MYC alters the efficiency and quality of mRNA translation into …

Control of HIV-1 gene expression by SR proteins

C Mahiet, CM Swanson - Biochemical Society Transactions, 2016 - portlandpress.com
Cellular proteins are required for all steps of human immunodeficiency virus type 1 (HIV-1)
gene expression including transcription, splicing, 3′-end formation/polyadenylation …

[HTML][HTML] Identification of diverse defense mechanisms in rainbow trout red blood cells in response to halted replication of VHS virus

I Nombela, S Puente-Marin, V Chico, AJ Villena… - …, 2017 - ncbi.nlm.nih.gov
Background: It has been described that fish nucleated red blood cells (RBCs) generate a
wide variety of immune-related gene transcripts when viruses highly replicate inside them …

Proteomic and Phosphoproteomic Analysis in Tobacco Mosaic Virus-Infected Tobacco (Nicotiana tabacum)

ZS Lu, QS Chen, QX Zheng, JJ Shen, ZP Luo, K Fan… - Biomolecules, 2019 - mdpi.com
Tobacco mosaic virus (TMV) is a common source of biological stress that significantly affects
plant growth and development. It is also useful as a model in studies designed to clarify the …

Identification of conserved, primary sequence motifs that direct retrovirus RNA fate

G Singh, BD Rife, B Seufzer, M Salemi… - Nucleic Acids …, 2018 - academic.oup.com
Precise stoichiometry of genome-length transcripts and alternatively spliced mRNAs is a
hallmark of retroviruses. We discovered short, guanosine and adenosine sequence motifs in …

[HTML][HTML] Host RNA-Binding Proteins as Regulators of HIV-1 Replication

S Giraldo-Ocampo, F Valiente-Echeverría, R Soto-Rifo - Viruses, 2024 - mdpi.com
RNA-binding proteins (RBPs) are cellular factors involved in every step of RNA metabolism.
During HIV-1 infection, these proteins are key players in the fine-tuning of viral and host …