The discovery of the role of non-coding RNAs (ncRNAs) in the onset and progression of
malignancies is a promising frontier of cancer genetics. It is clear that ncRNAs are …

Prior to the sequencing of the human genome, it was presumed that most of the DNA coded
for proteins. However, with the advent of next-generation sequencing, it has now been …

Long noncoding RNAs (lncRNAs) are emerging as key parts of multiple cellular pathways,
but their modes of action and how these are dictated by sequence remain unclear. lncRNAs …

Podocytes are known to play a determining role in the progression of proteinuric kidney
disease. N6-methyladenosine (m6A), as the most abundant chemical modification in …

The intestinal invasion of pathogenic microorganisms can have serious health
consequences. Recent evidence has shown that the N 6-methyladenosine (m6A) mRNA …

Neutrophil extracellular traps (NETs) assist pathogen clearance, while excessive NETs
formation is associated with exacerbated inflammatory responses and tissue injury in acute …

The transcription factor ΔNp63 regulates epithelial stem cell function and maintains the
integrity of stratified epithelial tissues by acting as transcriptional repressor or activator …

Inflammatory signaling underlies many diseases, from arthritis to cancer. Our understanding
of inflammation has thus far been limited to the world of proteins, because we are only just …

Abstract N6‐methyladenosine (m6A) modification regulatory proteins are involved in the
development of many types of cancer. KIAA1429 serves as a scaffold in bridging the …

Backgroud Multiple myeloma (MM) is an incurable plasma cell malignancy in the bone
marrow (BM), while immunoglobulin D type of MM (IgD MM) is a very rare but most severe …