Background The availability of clinical and therapeutic data drawn from medical records and
administrative databases has entailed new opportunities for clinical and epidemiologic …

Purpose To evaluate the validity of operative information recorded in the Diagnosis
Procedure Combination (DPC) database, a national inpatient database including …

Background: Validation of recorded data is a prerequisite for studies that utilize
administrative databases. The present study evaluated the validity of diagnoses and …

Objective To examine national trends of pediatric epilepsy surgery usage in the United
States between 1997 and 2009. Methods We performed a serial cross‐sectional study of …

Purpose Large‐scale administrative health care databases are increasingly being utilized
for research. However, there has not been much literature that validated administrative data …

With the widespread use of electronic medical records and administrative claims databases,
analytic results from so‐called real‐world data have become increasingly important in …

Background The primary approach for defining disease in observational healthcare
databases is to construct phenotype algorithms (PAs), rule-based heuristics predicated on …

Objectives: To identify common methodological challenges and review relevant initiatives
related to the re-use of patient data collected in routine clinical care, as well as to analyze …

Objective To estimate the incidence of hospitalisation due to varicella zoster virus (VZV)
infection in patients treated with tumour necrosis factor (TNF) antagonists for inflammatory …

Background Worldwide, asthma is a leading cause of morbidity, mortality and economic
burden, with significant gender and racial disparities. However, little attention has been …