Antibiotics are the commonest cause of life-threatening immune-mediated drug reactions
that are considered off-target, including anaphylaxis, and organ-specific and severe …

Importance β-Lactam antibiotics are among the safest and most effective antibiotics. Many
patients report allergies to these drugs that limit their use, resulting in the use of broad …

Abstract Background Even though 8%‐25% of most populations studied globally are labeled
as penicillin allergic, most diagnoses of penicillin allergy are made in childhood and relate …

Background Penicillin allergies are associated with inferior patient and antimicrobial
stewardship outcomes. We implemented a whole-of-hospital program to assess the efficacy …

The penicillin allergy label has been consistently linked with deleterious effects that span the
health care spectrum, including suboptimal clinical outcomes, the emergence of bacterial …

Drug hypersensitivity reactions (DHRs) to intravenous drugs can be severe and might leave
patients and doctors in a difficult position where an essential treatment or intervention has to …

The overlabeling of pediatric antibiotic allergy represents a huge burden in society. Given
that up to 10% of the US population is labeled as penicillin allergic, it can be estimated that …

Background Having a penicillin allergy label associates with a higher risk for antibiotic
resistance and increased health care use. Objective We sought to assess the accuracy of …

Background Antibiotics are among the most commonly prescribed medications for children;
however, at least one-third of pediatric antibiotic prescriptions are unnecessary. National …

Abstract Purpose of Review An unconfirmed penicillin allergy is known to confer significant
risk to patients. Only a small minority of patients labeled with penicillin allergy will be …