Polyphosphate is a linear chain of phosphate residues and is present in organisms ranging
from bacteria to humans. Pathogens such as Mycobacterium tuberculosis accumulate …

Bacterial chemotaxis to prominent microbiota metabolites such as indole is important in the
formation of microbial communities in the gastrointestinal (GI) tract. However, the basis of …

The canonical chemotaxis network modulates the bias for a particular direction of rotation in
the bacterial flagellar motor to help the cell migrate toward favorable chemical environments …

The flagellar motor can spin in both counterclockwise (CCW) and clockwise (CW) directions.
The flagellar motor consists of a rotor and multiple stator units, which act as a proton …

Switching of flagellar motor rotation sense dictates bacterial chemotaxis. Multi-subunit FliM-
FliG rotor rings couple signal protein binding in FliM with reversal of a distant FliG C-terminal …

Fluorescent fusion proteins open a direct and unique window onto protein function.
However, they also introduce the risk of perturbation of the function of the native protein …

Indole is a major component of the bacterial exometabolome, and the mechanisms for its
wide-ranging effects on bacterial physiology are biomedically significant, although they …

Escherichia coli swarm on semi-solid surfaces with the aid of flagella. It has been
hypothesized that swarmer cells overcome the increased viscous drag near surfaces by …

The bacterial flagellar motor (BFM) is a molecular machine that rotates the helical filaments
and propels the bacteria swimming toward favorable conditions. In our previous works, we …

Fumarate, an electron acceptor in anaerobic respiration of Escherichia coli, has an
additional function of assisting the flagellar motor to shift from counterclockwise to clockwise …