[HTML][HTML] Polarization-sensitive second harmonic generation microscopy for investigations of diseased collagenous tissues

R Cisek, A Joseph, MA Harvey, D Tokarz - Frontiers in Physics, 2021 - frontiersin.org
The advancement of non-invasive quantitative optical diagnosis techniques such as
polarization-sensitive second harmonic generation microscopy (PSHG) for diseases such as …

[HTML][HTML] Label-free non-linear multimodal optical microscopy—basics, development, and applications

N Mazumder, NK Balla, GY Zhuo, YV Kistenev… - Frontiers in …, 2019 - frontiersin.org
Non-linear optical (NLO) microscopy has proven to be a powerful tool especially for tissue
imaging with sub-cellular resolution, high penetration depth, endogenous contrast …

[HTML][HTML] In vivo two-photon microscopy of the human eye

FJ Ávila, A Gambín, P Artal, JM Bueno - Scientific reports, 2019 - nature.com
Abstract Two-photon (2P) microscopy is a powerful tool for imaging and exploring label-free
biological tissues at high resolution. Although this type of microscopy has been …

Blind deconvolution of second harmonic microscopy images of the living human eye

RM Martínez-Ojeda, LM Mugnier, P Artal… - Biomedical optics …, 2023 - opg.optica.org
Second harmonic generation (SHG) imaging microscopy of thick biological tissues is
affected by the presence of aberrations and scattering within the sample. Moreover …

Quantification of collagen fiber structure using second harmonic generation imaging and two‐dimensional discrete Fourier transform analysis: Application to the …

JK Pijanka, PP Markov, D Midgett… - Journal of …, 2019 - Wiley Online Library
Second harmonic generation (SHG) microscopy is widely used to image collagen fiber
microarchitecture due to its high spatial resolution, optical sectioning capabilities and …

Quantitative second harmonic generation microscopy for the structural characterization of capsular collagen in thyroid neoplasms

R Hristu, LG Eftimie, SG Stanciu, DE Tranca… - Biomedical optics …, 2018 - opg.optica.org
Quantitative second harmonic generation microscopy was used to investigate collagen
organization in the fibrillar capsules of human benign and malignant thyroid nodules. We …

[HTML][HTML] Quantitative evaluation of the human vocal fold extracellular matrix using multiphoton microscopy and optical coherence tomography

F Benboujja, C Hartnick - Scientific Reports, 2021 - nature.com
Identifying distinct normal extracellular matrix (ECM) features from pathology is of the
upmost clinical importance for laryngeal diagnostics and therapy. Despite remarkable …

Second harmonic generation microscopy: a tool for quantitative analysis of tissues

JM Bueno, FJ Ávila, P Artal - Microscopy and Analysis, 2016 - books.google.com
Second harmonic generation (SHG) is a second-order non-linear optical process produced
in birefringent crystals or in biological tissues with non-centrosymmetric structure such as …

Label-free multimodal nonlinear optical microscopy for biomedical applications

GY Zhuo, S KU, S KM, YV Kistenev, FJ Kao… - Journal of Applied …, 2021 - pubs.aip.org
This paper addresses the application of multimodal nonlinear optical (MNLO) microscopy to
clinical research within the context of label-free non-invasive molecular imaging. Here, a …

High-speed collagen fiber modeling and orientation quantification for optical coherence tomography imaging

JP McLean, Y Gan, TH Lye, D Qu, HH Lu… - Optics …, 2019 - opg.optica.org
Quantifying collagen fiber architecture has clinical and scientific relevance across a variety
of tissue types and adds functionality to otherwise largely qualitative imaging modalities …