The effect of metal ions (Fe, Co, Ni, and Cu) on the molecular-structural, protein binding, and cytotoxic properties of metal pyridoxal-thiosemicarbazone complexes
Thiosemicarbazones and their transition metal complexes are biologically active
compounds and anticancer agents with versatile structural properties. In this contribution …
compounds and anticancer agents with versatile structural properties. In this contribution …
Identification and interaction mechanism of protein corona on silver nanoparticles with different sizes and the cellular responses
With the potential biomedical applications of nanomaterials such as silver nanoparticles
(SNPs), nanotoxicity concerns are growing, and the importance of NP and protein …
(SNPs), nanotoxicity concerns are growing, and the importance of NP and protein …
Inhibitory mechanism of epicatechin gallate on tyrosinase: Inhibitory interaction, conformational change and computational simulation
X Song, X Hu, Y Zhang, J Pan, D Gong, G Zhang - Food & function, 2020 - pubs.rsc.org
The inhibition mechanism of epicatechin gallate (ECG) on tyrosinase was investigated by
multispectroscopic techniques combined with molecular docking and molecular dynamics …
multispectroscopic techniques combined with molecular docking and molecular dynamics …
Comparative assessment of 9-bromo noscapine ionic liquid and noscapine: Synthesis, in-vitro studies plus computational & biophysical evaluation with human …
S Sewariya, H Sehrawat, N Mishra, MB Singh… - International Journal of …, 2023 - Elsevier
Noscapine is a proficient anticancer drug active against wide variety of tumors including
lung cancer. Over time, several noscapine analogues have been assessed to maximize the …
lung cancer. Over time, several noscapine analogues have been assessed to maximize the …
Albumin roles in developing anticancer compounds
AG Ribeiro, JEF Alves, JCS Soares… - Medicinal Chemistry …, 2021 - Springer
Albumin is an abundant protein in nature with several biological functions. In the human
body, both in health and in illness, its transport function is highlighted by the binding to …
body, both in health and in illness, its transport function is highlighted by the binding to …
Unveiling interaction mechanisms between myricitrin and human serum albumin: Insights from multi-spectroscopic, molecular docking and molecular dynamic …
T Niu, X Zhu, D Zhao, H Li, P Yan, L Zhao… - … Acta Part A: Molecular …, 2023 - Elsevier
Myricitrin is a natural polyhydroxy flavonoid and is mainly derived from the bark and leaves
of the Chinese Bayberry tree (Myrica rubra). It has different pharmacological activities …
of the Chinese Bayberry tree (Myrica rubra). It has different pharmacological activities …
A comprehensive biophysical and theoretical study on the binding of dexlansoprazole with human serum albumin
Pharmacokinetics, pharmacodynamics, and therapeutic activity of drugs are defined by the
affinities between the drug and biological macromolecules through molecular recognition …
affinities between the drug and biological macromolecules through molecular recognition …
Investigation of binary and ternary systems of human serum albumin with oxyresveratrol/piceatannol and/or mitoxantrone by multipectroscopy, molecular docking and …
T Liu, M Liu, Q Guo, Y Liu, Y Zhao, Y Wu, B Sun… - Journal of Molecular …, 2020 - Elsevier
The combined application of polyphenols and anticancer drugs may be of great help to
current cancer treatment. In this paper, the individual and combined interactions of …
current cancer treatment. In this paper, the individual and combined interactions of …
Binding affinity and mechanism of six PFAS with human serum albumin: Insights from multi-spectroscopy, DFT and molecular dynamics approaches
M Peng, Y Xu, Y Wu, X Cai, W Zhang, L Zheng, E Du… - Toxics, 2024 - mdpi.com
Per-and Polyfluoroalkyl Substances (PFAS) bioaccumulate in the human body, presenting
potential health risks and cellular toxicity. Their transport mechanisms and interactions with …
potential health risks and cellular toxicity. Their transport mechanisms and interactions with …
Multi-spectroscopic and molecular docking studies of human serum albumin interactions with sulfametoxydiazine and sulfamonomethoxine
T Liao, Y Zhang, X Huang, Z Jiang, X Tuo - Spectrochimica Acta Part A …, 2021 - Elsevier
Sulfonamides are a kind of antibiotics which have been widely used as feed additives for
livestock and poultry. However, sulfa drugs have raised worldwide concerns because of …
livestock and poultry. However, sulfa drugs have raised worldwide concerns because of …