The role of microbiota in health and diseases is being highlighted by numerous studies
since its discovery. Depending on the localized regions, microbiota can be classified into …

Epithelial tight junctions define the paracellular permeability of the intestinal barrier.
Molecules can cross the tight junctions via two distinct size-selective and charge-selective …

Integration of sensory and molecular inputs from the environment shapes animal behaviour.
A major site of exposure to environmental molecules is the gastrointestinal tract, in which …

The brain and gastrointestinal tract are critical sensory organs responsible for detecting,
relaying, integrating, and responding to signals derived from the internal and external …

The human body is full of an extensive number of commensal microbes, consisting of
bacteria, viruses, and fungi, collectively termed the human microbiome. The initial …

The intestinal barrier protects the host against gut microbes, food antigens, and toxins
present in the gastrointestinal tract. However, gut barrier integrity can be affected by intrinsic …

Maternal health during pregnancy plays a major role in shaping health and disease risks in
the offspring. The maternal immune activation hypothesis proposes that inflammatory …

Microbiotas are a malleable part of ecosystems, including the human ecosystem.
Microorganisms affect not only the chemistry of their specific niche, such as the human gut …

There is increasing interest in the potential contribution of the gut microbiome to autism
spectrum disorder (ASD). However, previous studies have been underpowered and have …

In a striking display of trans-kingdom symbiosis, gut bacteria cooperate with their animal
hosts to regulate the development and function of the immune, metabolic and nervous …