A review of current trends with type 2 diabetes epidemiology, aetiology, pathogenesis, treatments and future perspectives

J Reed, S Bain, V Kanamarlapudi - Diabetes, Metabolic Syndrome …, 2021 - Taylor & Francis
Abstract Type 2 diabetes (T2D), which has currently become a global pandemic, is a
metabolic disease largely characterised by impaired insulin secretion and action. Significant …

The Lancet Commission on diabetes: using data to transform diabetes care and patient lives

JCN Chan, LL Lim, NJ Wareham, JE Shaw, TJ Orchard… - The Lancet, 2020 - thelancet.com
Executive summary 2020 will go down in history as the year when the global community was
awakened to the fragility of human health and the interdependence of the ecosystem …

Obesity as a multisystem disease: Trends in obesity rates and obesity‐related complications

S Sarma, S Sockalingam, S Dash - Diabetes, Obesity and …, 2021 - Wiley Online Library
Obesity is a chronic multisystem disease associated with increased morbidity and mortality.
The increasing prevalence of obesity makes it a major healthcare challenge across both …

2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: executive summary: a report of the …

SM Grundy, NJ Stone, AL Bailey, C Beam, KK Birtcher… - Circulation, 2019 - Am Heart Assoc
The recommendations listed in the present guideline are, whenever possible, evidence
based. An initial extensive evidence review, which included literature derived from research …

2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: a report of the American College of …

SM Grundy, NJ Stone, AL Bailey, C Beam, KK Birtcher… - Circulation, 2019 - Am Heart Assoc
The American Heart Association requests that this document be cited as follows: Grundy SM,
Stone NJ, Bailey AL, Beam C, Birtcher KK, Blumenthal RS, Braun LT, de Ferranti S, Faiella …

Identification of type 2 diabetes loci in 433,540 East Asian individuals

CN Spracklen, M Horikoshi, YJ Kim, K Lin, F Bragg… - Nature, 2020 - nature.com
Meta-analyses of genome-wide association studies (GWAS) have identified more than 240
loci that are associated with type 2 diabetes (T2D),; however, most of these loci have been …

[HTML][HTML] Epidemiology of diabetes and diabetic complications in China

RCW Ma - Diabetologia, 2018 - Springer
Abstract The People's Republic of China (herein referred to as China) has witnessed one of
the most dramatic rises in diabetes prevalence anywhere in the world. The latest …

ISPAD Clinical Practice Consensus Guidelines 2022: Type 2 diabetes in children and adolescents

AS Shah, PS Zeitler, J Wong, AS Pena… - Pediatric …, 2022 - Wiley Online Library
Since the 2018 ISPAD guidelines on this topic, follow‐up of large cohorts from around the
globe have continued informing the current incidence and prevalence of co‐morbidities and …

[HTML][HTML] Environmental/lifestyle factors in the pathogenesis and prevention of type 2 diabetes

H Kolb, S Martin - BMC medicine, 2017 - Springer
Background Environmental and lifestyle changes, in addition to the ageing of populations,
are generally believed to account for the rapid global increase in type 2 diabetes prevalence …

[PDF][PDF] Global Burden of Disease Study 2019 suggests that metabolic risk factors are the leading drivers of the burden of ischemic heart disease

W Wang, M Hu, H Liu, X Zhang, H Li, F Zhou, YM Liu… - Cell metabolism, 2021 - cell.com
Metabolic dysfunction is becoming a predominant risk for the development of many
comorbidities. Ischemic heart disease (IHD) still imposes the highest disease burden among …