The inflammatory chemokines CXCL9, CXCL10, and CXCL11 are predominantly induced
by interferon (IFN)-γ and share an exclusive chemokine receptor named CXC chemokine …

Metastasis still represents the primary cause of cancer morbidity and mortality worldwide.
Chemokine signalling contributes to the overall process of cancer growth and metastasis …

The important role of macrophages in host defense against a variety of pathogens has long
been recognized and has been documented and reviewed in numerous publications …

The phagocytes of the innate immune system, macrophages and neutrophils, contribute to
antibacterial defense, but their functional specialization and cooperation is unclear. Here …

This review focuses on the construction and application of structural chemokine receptor
models for the elucidation of molecular determinants of chemokine receptor modulation and …

First thought to orchestrate exclusively leukocyte trafficking, chemokines are now
acknowledged for their multiple roles in the regulation of cell proliferation, differentiation …

The G protein-coupled receptor (GPCR) CXC chemokine receptor 3 (CXCR3) is a potential
drug target that mediates signaling involved in cancer metastasis and inflammatory …

The chemotaxis of CD4+ type 1 helper cells and CD8+ cytotoxic lymphocytes, guided by
interferon-inducible CXC chemokine 9–11 (CXCL9–11) and CXC chemokine receptor 3 …

Atypical chemokine receptors (ACKRs) form a small subfamily of receptors (ACKR1–4)
unable to trigger G protein-dependent signaling in response to their ligands. They do …

Simple Summary The atypical chemokine receptor ACKR2 plays an important role in the
tumour microenvironment. It has long been considered as a scavenger of inflammatory …