Global threat of carbapenem-resistant gram-negative bacteria

SS Jean, D Harnod, PR Hsueh - Frontiers in cellular and infection …, 2022 - frontiersin.org
Infections caused by multidrug-resistant (MDR) and extensively drug-resistant (XDR) Gram-
negative bacteria (GNB), including carbapenem-resistant (CR) Enterobacterales (CRE; …

Insight into Acinetobacter baumannii: pathogenesis, global resistance, mechanisms of resistance, treatment options, and alternative modalities

M Asif, IA Alvi, SU Rehman - Infection and drug resistance, 2018 - Taylor & Francis
Acinetobacter baumannii, once considered a low-category pathogen, has emerged as an
obstinate infectious agent. The scientific community is paying more attention to this …

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock: 2016

A Rhodes, LE Evans, W Alhazzani, MM Levy… - Intensive care …, 2017 - Springer
Objective To provide an update to “Surviving Sepsis Campaign Guidelines for Management
of Sepsis and Septic Shock: 2012”. Design A consensus committee of 55 international …

Mechanisms of antimicrobial resistance in Gram-negative bacilli

É Ruppé, PL Woerther, F Barbier - Annals of intensive care, 2015 - Springer
The burden of multidrug resistance in Gram-negative bacilli (GNB) now represents a daily
issue for the management of antimicrobial therapy in intensive care unit (ICU) patients. In …

Update on the antibiotic resistance crisis

GM Rossolini, F Arena, P Pecile, S Pollini - Current opinion in …, 2014 - Elsevier
Highlights•The antibiotic resistance crisis is jeopardizing feasibility of medical practices.•The
antibiotic resistance crisis is more serious with Gram-negative pathogens.•XDR phenotypes …

Tackling threats and future problems of multidrug-resistant bacteria

E Medina, DH Pieper - How to overcome the antibiotic crisis: facts …, 2016 - Springer
With the advent of the antibiotic era, the overuse and inappropriate consumption and
application of antibiotics have driven the rapid emergence of multidrug-resistant pathogens …

Antibiotic hybrids: the next generation of agents and adjuvants against Gram-negative pathogens?

R Domalaon, T Idowu, GG Zhanel… - Clinical microbiology …, 2018 - Am Soc Microbiol
The global incidence of drug-resistant Gram-negative bacillary infections has been
increasing, and there is a dire need to develop novel strategies to overcome this problem …

Clinical and pathophysiological overview of Acinetobacter infections: a century of challenges

D Wong, TB Nielsen, RA Bonomo… - Clinical microbiology …, 2017 - Am Soc Microbiol
Acinetobacter is a complex genus, and historically, there has been confusion about the
existence of multiple species. The species commonly cause nosocomial infections …

Molecular mechanisms of sulbactam antibacterial activity and resistance determinants in Acinetobacter baumannii

WF Penwell, AB Shapiro, RA Giacobbe… - Antimicrobial agents …, 2015 - Am Soc Microbiol
Sulbactam is a class A β-lactamase inhibitor with intrinsic whole-cell activity against certain
bacterial species, including Acinetobacter baumannii. The clinical use of sulbactam for A …

[PDF][PDF] S3-leitlinie sepsis–prävention, diagnose, therapie und nachsorge

FM Brunkhorst, MA Weigand, M Pletz… - 2020 - publications.goettingen-research …
BeieinerSepsishandeltessichumeinelebens… Organdysfunktion ausgelöst durch eine
Infektion, die mit einer Regulationsstörung beim Wirt einhergeht. Ähnlich wie bei …