Advancement in leishmaniasis diagnosis and therapeutics: An update
Leishmaniasis is regarded as a neglected tropical disease by World Health Organization
(WHO) and is ranked next to malaria as the deadliest protozoan disease. The primary …
(WHO) and is ranked next to malaria as the deadliest protozoan disease. The primary …
Liposomal amphotericin B for treatment of leishmaniasis: from the identification of critical physicochemical attributes to the design of effective topical and oral …
F Frézard, MMG Aguiar, LAM Ferreira, GS Ramos… - Pharmaceutics, 2022 - mdpi.com
The liposomal amphotericin B (AmB) formulation, AmBisome®, still represents the best
therapeutic option for cutaneous and visceral leishmaniasis. However, its clinical efficacy …
therapeutic option for cutaneous and visceral leishmaniasis. However, its clinical efficacy …
Tackling drug resistance and other causes of treatment failure in leishmaniasis
GJ Wijnant, F Dumetz, L Dirkx, D Bulté… - Frontiers in Tropical …, 2022 - frontiersin.org
Leishmaniasis is a tropical infectious disease caused by the protozoan Leishmania parasite.
The disease is transmitted by female sand flies and, depending on the infecting parasite …
The disease is transmitted by female sand flies and, depending on the infecting parasite …
Effects of n-butanol extract of Pulsatilla decoction on the NLRP3 inflammasome in macrophages infected with Candida albicans
K Hu, H Zhang, G Shi, B Wang, D Wu, J Shao… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Pulsatilla decoction is a traditional Chinese medicine from
Shang Han Lun that has been reported to have therapeutic efficacy in vulvovaginal …
Shang Han Lun that has been reported to have therapeutic efficacy in vulvovaginal …
Cutaneous/mucocutaneous leishmaniasis treatment for wound healing: classical versus new treatment approaches
P Severino, W Santana, ES Lisboa, VLS Santos… - Microbiology …, 2022 - mdpi.com
Cutaneous leishmaniasis (CL) and mucocutaneous leishmaniasis (ML) show clinical
spectra that can range from a localized lesion (with a spontaneous healing process) to …
spectra that can range from a localized lesion (with a spontaneous healing process) to …
Nanomedicine-based strategies to improve treatment of cutaneous leishmaniasis
N Goonoo, MA Laetitia Huët… - Royal Society …, 2022 - royalsocietypublishing.org
Nanomedicine strategies were first adapted and successfully translated to clinical
application for diseases, such as cancer and diabetes. These strategies would no doubt …
application for diseases, such as cancer and diabetes. These strategies would no doubt …
Interferon lambda restricts herpes simplex virus skin disease by suppressing neutrophil-mediated pathology
Type III interferons (IFN-λ) are antiviral and immunomodulatory cytokines that have been
best characterized in respiratory and gastrointestinal infections, but the effects of IFN-λ …
best characterized in respiratory and gastrointestinal infections, but the effects of IFN-λ …
Neutrophil-mediated hypoxia drives pathogenic CD8 T cell responses in cutaneous leishmaniasis
EA Fowler, CF Amorim, K Mostacada… - The Journal of …, 2024 - Am Soc Clin Investig
Cutaneous leishmaniasis caused by Leishmania parasites exhibits a wide range of clinical
manifestations. Although parasites influence disease severity, cytolytic CD8 T cell responses …
manifestations. Although parasites influence disease severity, cytolytic CD8 T cell responses …
[HTML][HTML] The immunomicrotope of Leishmania control and persistence
Leishmania is an intracellular protozoan transmitted by sand fly vectors; it causes
cutaneous, mucocutaneous, or visceral disease. Its growth and survival are impeded by type …
cutaneous, mucocutaneous, or visceral disease. Its growth and survival are impeded by type …
The potential role of protein disulfide isomerases (PDIs) during parasitic infections: a focus on Leishmania spp
M Dousti, M Hosseinpour, ND Ghasemi… - Pathogens and …, 2023 - academic.oup.com
Leishmaniasis is a group of vector-borne diseases caused by intracellular protozoan
parasites belonging to the genus Leishmania. Leishmania parasites can employ different …
parasites belonging to the genus Leishmania. Leishmania parasites can employ different …