[HTML][HTML] Endothelial dysfunction and immunothrombosis as key pathogenic mechanisms in COVID-19
A Bonaventura, A Vecchié, L Dagna… - Nature Reviews …, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) is a clinical syndrome caused by infection
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients with severe …
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients with severe …
[HTML][HTML] Neutrophil: a cell with many roles in inflammation or several cell types?
C Rosales - Frontiers in physiology, 2018 - frontiersin.org
Neutrophils are the most abundant leukocytes in the circulation, and have been regarded as
first line of defense in the innate arm of the immune system. They capture and destroy …
first line of defense in the innate arm of the immune system. They capture and destroy …
Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome
COVID-19 affects millions of patients worldwide, with clinical presentation ranging from
isolated thrombosis to acute respiratory distress syndrome (ARDS) requiring ventilator …
isolated thrombosis to acute respiratory distress syndrome (ARDS) requiring ventilator …
[HTML][HTML] Curcumin as a potential treatment for COVID-19
Coronavirus disease 2019 (COVID-19) is an infectious disease that rapidly spread
throughout the world leading to high mortality rates. Despite the knowledge of previous …
throughout the world leading to high mortality rates. Despite the knowledge of previous …
[HTML][HTML] Role of myeloperoxidase and oxidant formation in the extracellular environment in inflammation-induced tissue damage
CL Hawkins, MJ Davies - Free Radical Biology and Medicine, 2021 - Elsevier
The heme peroxidase family generates a battery of oxidants both for synthetic purposes, and
in the innate immune defence against pathogens. Myeloperoxidase (MPO) is the most …
in the innate immune defence against pathogens. Myeloperoxidase (MPO) is the most …
Inflamm-ageing: the role of inflammation in age-dependent cardiovascular disease
L Liberale, F Montecucco, JC Tardif… - European heart …, 2020 - academic.oup.com
The ongoing worldwide increase in life expectancy portends a rising prevalence of age-
related cardiovascular (CV) diseases in the coming decades that demands a deeper …
related cardiovascular (CV) diseases in the coming decades that demands a deeper …
The role of myeloperoxidase in biomolecule modification, chronic inflammation, and disease
MJ Davies, CL Hawkins - Antioxidants & redox signaling, 2020 - liebertpub.com
Significance: The release of myeloperoxidase (MPO) by activated leukocytes is critical in
innate immune responses. MPO produces hypochlorous acid (HOCl) and other strong …
innate immune responses. MPO produces hypochlorous acid (HOCl) and other strong …
Oxidative stress in autoimmune rheumatic diseases
The management of patients with autoimmune rheumatic diseases such as rheumatoid
arthritis (RA) remains a significant challenge. Often the rheumatologist is restricted to …
arthritis (RA) remains a significant challenge. Often the rheumatologist is restricted to …
[HTML][HTML] Autoantibodies stabilize neutrophil extracellular traps in COVID-19
Y Zuo, S Yalavarthi, SA Navaz, CK Hoy, A Harbaugh… - JCI insight, 2021 - ncbi.nlm.nih.gov
The release of neutrophil extracellular traps (NETs) by hyperactive neutrophils is recognized
to play an important role in the thromboinflammatory milieu inherent to severe presentations …
to play an important role in the thromboinflammatory milieu inherent to severe presentations …
[HTML][HTML] Age-related cerebral small vessel disease and inflammaging
T Li, Y Huang, W Cai, X Chen, X Men, T Lu, A Wu… - Cell death & …, 2020 - nature.com
The continued increase in global life expectancy predicts a rising prevalence of age-related
cerebral small vessel diseases (CSVD), which requires a better understanding of the …
cerebral small vessel diseases (CSVD), which requires a better understanding of the …