The multifaceted role of aquaporin-9 in health and its potential as a clinical biomarker
IV da Silva, S Garra, G Calamita, G Soveral - Biomolecules, 2022 - mdpi.com
Aquaporins (AQPs) are transmembrane channels essential for water, energy, and redox
homeostasis, with proven involvement in a variety of pathophysiological conditions such as …
homeostasis, with proven involvement in a variety of pathophysiological conditions such as …
Aquaporins: New players in breast cancer progression and treatment response
V Charlestin, D Fulkerson, CE Arias Matus… - Frontiers in …, 2022 - frontiersin.org
Aquaporins (AQPs) are a family of small transmembrane proteins that selectively transport
water and other small molecules and ions following an osmotic gradient across cell plasma …
water and other small molecules and ions following an osmotic gradient across cell plasma …
Aquaglyceroporins: drug targets for metabolic diseases?
G Calamita, J Perret, C Delporte - Frontiers in physiology, 2018 - frontiersin.org
Aquaporins (AQPs) are a family of transmembrane channel proteins facilitating the transport
of water, small solutes, and gasses across biological membranes. AQPs are expressed in all …
of water, small solutes, and gasses across biological membranes. AQPs are expressed in all …
AQP9 is a prognostic factor for kidney cancer and a promising indicator for M2 TAM polarization and CD8+ T-cell recruitment
J Jing, J Sun, Y Wu, N Zhang, C Liu, S Chen… - Frontiers in …, 2021 - frontiersin.org
Background It is undeniable that the tumor microenvironment (TME) plays an indispensable
role in the progression of kidney renal clear cell carcinoma (KIRC). However, the precise …
role in the progression of kidney renal clear cell carcinoma (KIRC). However, the precise …
[HTML][HTML] AQP9 transports lactate in tumor-associated macrophages to stimulate an M2-like polarization that promotes colon cancer progression
Y Shi, M Yasui, M Hara-Chikuma - Biochemistry and Biophysics Reports, 2022 - Elsevier
Macrophages play a major role in the immune defense against pathogenic factors; however,
they can lead to tumor exacerbation and metastasis, as the tumor microenvironment (TME) …
they can lead to tumor exacerbation and metastasis, as the tumor microenvironment (TME) …
[HTML][HTML] Arsenic metabolites; selenium; and AS3MT, MTHFR, AQP4, AQP9, SELENOP, INMT, and MT2A polymorphisms in Croatian-Slovenian population from PHIME …
A Stajnko, Z Šlejkovec, D Mazej, A France-Štiglic… - Environmental …, 2019 - Elsevier
The relationships between inorganic arsenic (iAs) metabolism, selenium (Se) status, and
genetic polymorphisms of various genes, commonly studied in populations exposed to high …
genetic polymorphisms of various genes, commonly studied in populations exposed to high …
Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei
Mutations in the Trypanosoma brucei aquaporin AQP2 are associated with resistance to
pentamidine and melarsoprol. We show that TbAQP2 but not TbAQP3 was positively …
pentamidine and melarsoprol. We show that TbAQP2 but not TbAQP3 was positively …
Aquaporins display a diversity in their substrates
R Sachdeva, P Priyadarshini, S Gupta - The Journal of membrane biology, 2023 - Springer
Aquaporins constitute a family of transmembrane proteins that function to transport water
and other small solutes across the cell membrane. Aquaporins family members are found in …
and other small solutes across the cell membrane. Aquaporins family members are found in …
Integrated multiomics analysis reveals changes in liver physiological function in Aqp9 gene knockout mice
Q Cheng, J Zhang, H Ding, Z Wang, J Fang… - International Journal of …, 2023 - Elsevier
Abstract Aquaporin 9 (AQP9) is the main channel by which blood glycerol enters the liver,
where it plays key roles in osmotic pressure regulation and energy metabolism. Previous …
where it plays key roles in osmotic pressure regulation and energy metabolism. Previous …
[HTML][HTML] Differential expressions of aquaporin subtypes in female reproductive tract of mice
JW Im, CY Lee, DH Kim, HR Bae - Development & Reproduction, 2020 - ncbi.nlm.nih.gov
Although many aquaporin (AQP) transcripts have been demonstrated to express in the
female reproductive tract, the defined localizations and functions of AQP subtype proteins …
female reproductive tract, the defined localizations and functions of AQP subtype proteins …