The right ventricle and its stress response is perhaps the most important arbiter of survival in
patients with pulmonary hypertension of many causes. The physiology of the …

Respiratory diseases in both children and adults are a major cause of morbidity and
mortality worldwide. Despite decades of research, mechanisms underlying the broad …

Premature birth is associated with endothelial and mitochondrial dysfunction, and chronic
oxidative stress, which might impair the physiological responses to acute altitude exposure …

Evidence suggests that preterm birth is associated with an impaired physical fitness later in
life, but whether these effects are already visible since early childhood remains unknown …

Purpose Premature birth induces long-term sequelae on the cardiopulmonary system,
leading to reduced exercise capacity. However, the mechanisms of this functional …

Background Premature birth (PTB) increases the long-term risk of diseases such as
hypertension, heart disease, and diabetes in adulthood. It is an independent disease with …

Premature birth impairs cardiac and ventilatory responses to both hypoxia and hypercapnia,
but little is known about cerebrovascular responses. Both at sea level and after 2 days at …

Pre‐term birth is associated with physiological sequelae that persist into adulthood. In
particular, modulated ventilatory responsiveness to hypoxia and hypercapnia has been …

Background A negative impact of premature birth on health in adulthood is well established.
However, it is not clear whether healthy adults who were born prematurely but have similar …

Global premature birth rates are continuing to increase such that 5-18% of all deliveries now
27 occur before the 37th week of gestation (20). Improvements in perinatal care have …