Therapeutic peptides: current applications and future directions

L Wang, N Wang, W Zhang, X Cheng, Z Yan… - Signal transduction and …, 2022 - nature.com
Peptide drug development has made great progress in the last decade thanks to new
production, modification, and analytic technologies. Peptides have been produced and …

Controlled drug delivery systems: current status and future directions

S Adepu, S Ramakrishna - Molecules, 2021 - mdpi.com
The drug delivery system enables the release of the active pharmaceutical ingredient to
achieve a desired therapeutic response. Conventional drug delivery systems (tablets …

Trends in peptide drug discovery

M Muttenthaler, GF King, DJ Adams… - Nature reviews Drug …, 2021 - nature.com
Since the introduction of insulin almost a century ago, more than 80 peptide drugs have
reached the market for a wide range of diseases, including diabetes, cancer, osteoporosis …

Polyphenol‐containing nanoparticles: synthesis, properties, and therapeutic delivery

Y Guo, Q Sun, FG Wu, Y Dai, X Chen - Advanced Materials, 2021 - Wiley Online Library
Polyphenols, the phenolic hydroxyl group‐containing organic molecules, are widely found in
natural plants and have shown beneficial effects on human health. Recently, polyphenol …

Enhanced tendon healing by a tough hydrogel with an adhesive side and high drug-loading capacity

BR Freedman, A Kuttler, N Beckmann, S Nam… - Nature biomedical …, 2022 - nature.com
Hydrogels that provide mechanical support and sustainably release therapeutics have been
used to treat tendon injuries. However, most hydrogels are insufficiently tough, release …

Design and applications of water-soluble coordination cages

EG Percástegui, TK Ronson, JR Nitschke - Chemical Reviews, 2020 - ACS Publications
Compartmentalization of the aqueous space within a cell is necessary for life. In similar
fashion to the nanometer-scale compartments in living systems, synthetic water-soluble …

Synthesis and biological application of polylactic acid

G Li, M Zhao, F Xu, B Yang, X Li, X Meng, L Teng… - Molecules, 2020 - mdpi.com
Over the past few decades, with the development of science and technology, the field of
biomedicine has rapidly developed, especially with respect to biomedical materials. Low …

Nucleic acid delivery for therapeutic applications

A Gupta, JL Andresen, RS Manan, R Langer - Advanced Drug Delivery …, 2021 - Elsevier
Recent medical advances have exploited the ability to address a given disease at the
underlying level of transcription and translation. These treatment paradigms utilize nucleic …

Medical micro/nanorobots in precision medicine

F Soto, J Wang, R Ahmed, U Demirci - Advanced science, 2020 - Wiley Online Library
Advances in medical robots promise to improve modern medicine and the quality of life.
Miniaturization of these robotic platforms has led to numerous applications that leverages …

Biomedical polymers: synthesis, properties, and applications

WH Chen, QW Chen, Q Chen, C Cui, S Duan… - Science China …, 2022 - Springer
Biomedical polymers have been extensively developed for promising applications in a lot of
biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis …