Non-alcoholic fatty liver disease (NAFLD) and its inflammatory form, non-alcoholic
steatohepatitis (NASH), have quickly risen to become the most prevalent chronic liver …

Cholesterol homeostasis has been implicated in the regulation of cellular and body
metabolism. Hence, deregulated cholesterol homeostasis leads to the development of many …

Notch has been implicated in human cancers and is a putative therapeutic target. However,
the regulation of Notch activation in the nucleus remains largely uncharacterized. Therefore …

Hepatocellular carcinoma (HCC) is a highly heterogeneous malignancy with high incidence,
recurrence, and metastasis rates. The emergence of immunotherapy has improved the …

Long non-coding RNAs (lncRNAs) are a class of RNA transcripts more than 200 nucleotides
in length that play crucial roles in cancer development and progression. With the rapid …

Significance: Cholesterol is a type of lipid that plays a crucial role in building and
maintaining cell membranes, producing certain hormones, and aiding in digestion. The two …

Simple Summary This review is focused on the research recently published in the field of
non-alcoholic fatty liver disease (NAFLD) or metabolic dysfunction-associated steatotic liver …

The macronutrients glucose, lipids, and amino acids are the major components that maintain
life. The ability of cells to sense and respond to fluctuations in these nutrients is a crucial …

Ferroptosis, a unique type of non-apoptotic cell death resulting from iron-dependent lipid
peroxidation, has a potential physiological function in tumor suppression, but its underlying …

Cuproptosis is a novel cell death mechanism caused by copper overload, with FDX1 serving
as the key regulator. LncRNAs are known to play a significant role in the aberrant regulation …