Studying the complex molecular mechanisms involved in traumatic brain injury (TBI) is
crucial for developing new therapies for TBI. Current treatments for TBI are primarily focused …

Alzheimer disease is the most prevalent form of dementia globally and is characterized
premortem by a gradual memory loss and deterioration of higher cognitive functions and …

Glutamate's role as a neurotransmitter at synapses has been known for 40 years, but
glutamate has since been shown to regulate neurogenesis, neurite outgrowth …

Traumatic brain injury (TBI) results in significant disability due to cognitive deficits
particularly in attention, learning and memory, and higher-order executive functions. The …

✓ Cerebral edema is caused by a variety of pathological conditions that affect the brain. It is
associated with two separate pathophysiological processes with distinct molecular and …

Cortical spreading depolarization (CSD) is a promising target for neuroprotective therapy in
traumatic brain injury (TBI). We explored the effect of NMDA receptor antagonism on …

The blood–brain barrier is a highly selective anatomical and functional interface allowing a
unique environment for neuro-glia networks. Blood–brain barrier dysfunction is common in …

Glutamate is the principal excitatory neurotransmitter in the brain. Knowledge of the
glutamatergic synapse has advanced enormously over the last 10 years, primarily through …

The present study examined the neuropathology of the lateral controlled cortical impact
(CCI) traumatic brain injury (TBI) model in mice utilizing the de Olmos silver staining method …

Preconditioning is a phenomenon in which brief episodes of a sublethal insult induce robust
protection against subsequent lethal injuries. Preconditioning has been observed in multiple …