The continued threat of emerging flaviviruses
TC Pierson, MS Diamond - Nature microbiology, 2020 - nature.com
Flaviviruses are vector-borne RNA viruses that can emerge unexpectedly in human
populations and cause a spectrum of potentially severe diseases including hepatitis …
populations and cause a spectrum of potentially severe diseases including hepatitis …
Combating mosquito-borne diseases using genetic control technologies
Mosquito-borne diseases, such as dengue and malaria, pose significant global health
burdens. Unfortunately, current control methods based on insecticides and environmental …
burdens. Unfortunately, current control methods based on insecticides and environmental …
Development of a confinable gene drive system in the human disease vector Aedes aegypti
Aedes aegypti is the principal mosquito vector for many arboviruses that increasingly infect
millions of people every year. With an escalating burden of infections and the relative failure …
millions of people every year. With an escalating burden of infections and the relative failure …
Inherently confinable split-drive systems in Drosophila
CRISPR-based gene-drive systems, which copy themselves via gene conversion mediated
by the homology-directed repair (HDR) pathway, have the potential to revolutionize vector …
by the homology-directed repair (HDR) pathway, have the potential to revolutionize vector …
Manipulating the destiny of wild populations using CRISPR
Genetic biocontrol aims to suppress or modify populations of species to protect public
health, agriculture, and biodiversity. Advancements in genome engineering technologies …
health, agriculture, and biodiversity. Advancements in genome engineering technologies …
Broad dengue neutralization in mosquitoes expressing an engineered antibody
With dengue virus (DENV) becoming endemic in tropical and subtropical regions worldwide,
there is a pressing global demand for effective strategies to control the mosquitoes that …
there is a pressing global demand for effective strategies to control the mosquitoes that …
A Review: Wolbachia-Based Population Replacement for Mosquito Control Shares Common Points with Genetically Modified Control Approaches
PS Yen, AB Failloux - Pathogens, 2020 - mdpi.com
The growing expansion of mosquito vectors has made mosquito-borne arboviral diseases a
global threat to public health, and the lack of licensed vaccines and treatments highlight the …
global threat to public health, and the lack of licensed vaccines and treatments highlight the …
Advances and challenges in synthetic biology for mosquito control
Mosquito-borne illnesses represent a significant global health peril, resulting in
approximately one million fatalities annually. West Nile, dengue, Zika, and malaria are …
approximately one million fatalities annually. West Nile, dengue, Zika, and malaria are …
Assessment of a split homing based gene drive for efficient knockout of multiple genes
Homing based gene drives (HGD) possess the potential to spread linked cargo genes into
natural populations and are poised to revolutionize population control of animals. Given that …
natural populations and are poised to revolutionize population control of animals. Given that …
Essential oils and their chemical constituents against Aedes aegypti L.(Diptera: Culicidae) larvae
TRSA Luz, LSS de Mesquita, FMM do Amaral… - Acta Tropica, 2020 - Elsevier
This review focused on the toxicity of essential oils and their constituents against Aedes
aegypti L.(Diptera, Culicidae) larvae, a key vector of important arboviral diseases, such as …
aegypti L.(Diptera, Culicidae) larvae, a key vector of important arboviral diseases, such as …