Transient receptor potential (TRP) channels are multifunctional signalling molecules with
many roles in sensory perception and cellular physiology. Therefore, it is not surprising that …

Transient receptor potential (TRP) channels are sensors for a variety of cellular and
environmental signals. Mammals express a total of 28 different TRP channel proteins, which …

Transient receptor potential (TRP) channels are a superfamily of non-selective cation
channels that act as polymodal sensors in many tissues throughout mammalian organisms …

The perception of nociceptive signals, which are translated into pain, plays a fundamental
role in the survival of organisms. Because pain is linked to a negative sensation, animals …

The topic of this chapter, transient receptor potential ankyrin 1 (TRPA1), is a calcium-
permeable nonselective cation channel that is a member of the TRP family expressed on …

Migraine is a debilitating neurological condition affecting millions of people worldwide. Until
a few years ago, preventive migraine treatments were based on molecules with pleiotropic …

The transient receptor potential ankyrin 1 (TRPA1), a member of the TRP superfamily of
channels, acts as 'polymodal cellular sensor'on primary sensory neurons where it mediates …

Background The treatment of neuropathic pain is still a major troublesome clinical problem.
The existing therapeutic drugs have limited analgesic effect and obvious adverse reactions …

Transient receptor potential ankyrin 1 (TRPA1) is a polymodal nonselective cation channel
sensitive to different physical and chemical stimuli. TRPA1 is associated with many …

Transient receptor potential ankyrin 1 (TRPA1) is a nonselective calcium-permeable ion
channel highly expressed in the primary sensory neurons functioning as a polymodal sensor …