[HTML][HTML] Nanotechnology based drug delivery systems for the treatment of anterior segment eye diseases

AL Onugwu, CS Nwagwu, OS Onugwu… - Journal of Controlled …, 2023 - Elsevier
Diseases affecting the anterior segment of the eye are the primary causes of vision
impairment and blindness globally. Drug administration through the topical ocular route is …

Liposomes as vehicles for topical ophthalmic drug delivery and ocular surface protection

JJ López-Cano… - Expert opinion on …, 2021 - Taylor & Francis
Introduction: The development of ophthalmic formulations able to deliver hydrophilic and
hydrophobic drugs to the inner structures of the eye and restore the preocular tear film has …

Advances in biodegradable nano-sized polymer-based ocular drug delivery

C Lynch, PPD Kondiah, YE Choonara, LC du Toit… - Polymers, 2019 - mdpi.com
The effective delivery of drugs to the eye remains a challenge. The eye has a myriad of
defense systems and physiological barriers that leaves ocular drug delivery systems with …

Molecular nature of ocular surface barrier function, diseases that affect it, and its relevance for ocular drug delivery

S Kaur, P Sohnen, S Swamynathan, Y Du, EM Espana… - The ocular …, 2023 - Elsevier
The structural and functional integrity of the ocular surface, a continuous epithelial structure
comprised of the cornea, the conjunctiva, and the ductal surface of the lacrimal as well as …

[HTML][HTML] Advancements in Ocular Therapy: A Review of Emerging Drug Delivery Approaches and Pharmaceutical Technologies

BR Giri, D Jakka, MA Sandoval, VR Kulkarni, Q Bao - Pharmaceutics, 2024 - mdpi.com
Eye disorders affect a substantial portion of the global population, yet the availability of
efficacious ophthalmic drug products remains limited. This can be partly ascribed to a …

[HTML][HTML] Restoring the oxidative balance in age-related diseases–An approach in glaucoma

PR Cáceres-Vélez, F Hui, J Hercus, B Bui… - Ageing Research …, 2022 - Elsevier
As human life expectancy increases, age-related health issues including neurodegenerative
diseases continue to rise. Regardless of genetic or environmental factors, many …

[HTML][HTML] Nanomedicine in glaucoma treatment; Current challenges and future perspectives

H Iqbal, A Razzaq, D Zhou, J Lou, R Xiao, F Lin… - Materials Today Bio, 2024 - Elsevier
Glaucoma presents a significant global health concern and affects millions of individuals
worldwide and predicted a high increase in prevalence of about 111 million by 2040. The …

Biopolymer-based nano-formulations for mitigation of ocular infections: a review

D Karati, S Mukherjee, S Singh, BG Prajapati, B Basu - Polymer Bulletin, 2024 - Springer
Ocular infirmities significantly influence a person's routine process by impairing vision to the
point of blindness. Effective ocular drug administration with significant bioavailability is …

Glaucoma: management and future perspectives for nanotechnology-based treatment modalities

NM El Hoffy, EAA Azim, RM Hathout, MA Fouly… - European journal of …, 2021 - Elsevier
Glaucoma, being asymptomatic for relatively late stage, is recognized as a worldwide cause
of irreversible vision loss. The eye is an impervious organ that exhibits natural anatomical …

Novel osmoprotective DOPC-DMPC liposomes loaded with antihypertensive drugs as potential strategy for glaucoma treatment

MA González-Cela-Casamayor, JJ López-Cano… - Pharmaceutics, 2022 - mdpi.com
Glaucoma is a group of chronic irreversible neuropathies that affect the retina and the optic
nerve. It is considered one of the leading causes of blindness in the world. Although it can …