Although early demonstration dates back to the mid-sixties, x-ray phase-contrast imaging
(XPCI) became hugely popular in the mid-90s, thanks to the advent of 3rd generation …

Imaging across different scales is essential for understanding healthy organ morphology
and pathophysiological changes. The macro-and microscale three-dimensional morphology …

Mortality in acute respiratory distress syndrome (ARDS) remains unacceptably high at
approximately 39%. One of the only treatments is supportive: mechanical ventilation …

Protective ventilation strategies for the injured lung currently revolve around the use of low
Vt, ostensibly to avoid volutrauma, together with positive end-expiratory pressure to increase …

Featured Application X-ray phase contrast and dark-field imaging have been recently
introduced in conventional systems. They have been demonstrated to outperform the …

In the pursuit of science, competitive ideas and debate are necessary means to attain
knowledge and expose our ignorance. To quote Murray Gell-Mann (1969 Nobel Prize …

A hallmark of ARDS is progressive shrinking of the 'baby lung,'now referred to as the
ventilator-induced lung injury (VILI)'vortex.'Reducing the risk of the VILI vortex is the goal of …

Phase-contrast X-ray lung imaging has broken new ground in preclinical respiratory
research by improving contrast at air/tissue interfaces. To minimize blur from respiratory …

Background The University of Southampton, in collaboration with the University Hospital
Southampton (UHS) NHS Foundation Trust and industrial partners, has been at the forefront …

The study of lung mechanics is important to futureproof resilience against potential novel
threats to lung health. Medical imaging provides insight to lung function. High-resolution …