Phenotyping male infertility in the mouse: how to get the most out of a 'non-performer'

CL Borg, KM Wolski, GM Gibbs… - Human reproduction …, 2010 - academic.oup.com
BACKGROUND Functional male gametes are produced through complex processes that
take place within the testis, epididymis and female reproductive tract. A breakdown at any of …

Antisperm contraceptive vaccines: where we are and where we are going?

RK Naz - American Journal of Reproductive Immunology, 2011 - Wiley Online Library
Citation Naz RK. Antisperm contraceptive vaccines: where we are and where we are going?
Am J Reprod Immunol 2011; 66: 5–12 This is a review of current status and future …

Mutant ZP1 in familial infertility

HL Huang, C Lv, YC Zhao, W Li, XM He… - … England Journal of …, 2014 - Mass Medical Soc
The human zona pellucida is composed of four glycoproteins (ZP1, ZP2, ZP3, and ZP4) and
has an important role in reproduction. Here we describe a form of infertility with an …

MicroRNA signature in various cell types of mouse spermatogenesis: evidence for stage‐specifically expressed miRNA‐221,‐203 and‐34b‐5p mediated …

L Smorag, Y Zheng, J Nolte, U Zechner… - Biology of the …, 2012 - Wiley Online Library
Background information Recently, it became apparent that microRNAs (miRNAs) can
regulate gene expression post‐transcriptionally. Despite the advances in identifying the …

Global human tissue profiling and protein network analysis reveals distinct levels of transcriptional germline-specificity and identifies target genes for male infertility

F Chalmel, A Lardenois, B Evrard, R Mathieu… - Human …, 2012 - academic.oup.com
BACKGROUND Mammalian spermatogenesis is a process that involves a complex
expression program in both somatic and germ cells present in the male gonad. A number of …

TMEM203 is a novel regulator of intracellular calcium homeostasis and is required for spermatogenesis

PB Shambharkar, M Bittinger, B Latario, ZH Xiong… - PLoS …, 2015 - journals.plos.org
Intracellular calcium signaling is critical for initiating and sustaining diverse cellular functions
including transcription, synaptic signaling, muscle contraction, apoptosis and fertilization …

Vaccine for human contraception targeting sperm Izumo protein and YLP12 dodecamer peptide

RK Naz - Protein Science, 2014 - Wiley Online Library
There is an urgent need to develop a better method of contraception which is non‐steroidal
and reversible to control world population explosion and unintended pregnancies …

[HTML][HTML] Male contraception: Another holy grail

FE Murdoch, E Goldberg - Bioorganic & medicinal chemistry letters, 2014 - Elsevier
The idea that men should participate in family planning by playing an active role in
contraception has become more acceptable in recent years. Up to the present the condom …

CFAP157 is a murine downstream effector of FOXJ1 that is specifically required for flagellum morphogenesis and sperm motility

M Weidemann, K Schuster-Gossler, M Stauber… - …, 2016 - journals.biologists.com
Motile cilia move extracellular fluids or mediate cellular motility. Their function is essential for
embryonic development, adult tissue homeostasis and reproduction throughout vertebrates …

The paralogs' enigma of germ-cell specific genes dispensable for fertility: the case of 19 oogenesin genes

J Castille, D Thépot, S Fouchécourt… - Biology of …, 2023 - academic.oup.com
Gene knockout experiments have shown that many genes are dispensable for a given
biological function. In this review, we make an assessment of male and female germ cell …