From evidence-based medicine to digital twin technology for predicting ventricular tachycardia in ischaemic cardiomyopathy
AGW de Lepper, CMA Buck… - Journal of the …, 2022 - royalsocietypublishing.org
Survivors of myocardial infarction are at risk of life-threatening ventricular tachycardias (VTs)
later in their lives. Current guidelines for implantable cardioverter defibrillators (ICDs) …
later in their lives. Current guidelines for implantable cardioverter defibrillators (ICDs) …
[HTML][HTML] A comprehensive and biophysically detailed computational model of the whole human heart electromechanics
While ventricular electromechanics is extensively studied in both physiological and
pathological conditions, four-chamber heart models have only been addressed recently; …
pathological conditions, four-chamber heart models have only been addressed recently; …
A mathematical model that integrates cardiac electrophysiology, mechanics, and fluid dynamics: Application to the human left heart
We propose a mathematical and numerical model for the simulation of the heart function that
couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and …
couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and …
[HTML][HTML] lifex: A flexible, high performance library for the numerical solution of complex finite element problems
PC Africa - SoftwareX, 2022 - Elsevier
Numerical simulations are ubiquitous in mathematics and computational science. Several
industrial and clinical applications entail modeling complex multiphysics systems that evolve …
industrial and clinical applications entail modeling complex multiphysics systems that evolve …
[HTML][HTML] A cardiac electromechanical model coupled with a lumped-parameter model for closed-loop blood circulation
We propose a novel mathematical and numerical model for cardiac electromechanics,
wherein biophysically detailed core models describe the different physical processes …
wherein biophysically detailed core models describe the different physical processes …
[HTML][HTML] 3D–0D closed-loop model for the simulation of cardiac biventricular electromechanics
Two crucial factors for accurate numerical simulations of cardiac electromechanics, which
are also essential to reproduce the synchronous activity of the heart, are:(i) accounting for …
are also essential to reproduce the synchronous activity of the heart, are:(i) accounting for …
lifex-cfd: An open-source computational fluid dynamics solver for cardiovascular applications
Computational fluid dynamics (CFD) is an important tool for the simulation of the
cardiovascular function and dysfunction. Due to the complexity of the anatomy, the …
cardiovascular function and dysfunction. Due to the complexity of the anatomy, the …
[HTML][HTML] The role of mechano-electric feedbacks and hemodynamic coupling in scar-related ventricular tachycardia
Abstract Mechano-electric feedbacks (MEFs), which model how mechanical stimuli are
transduced into electrical signals, have received sparse investigation by considering …
transduced into electrical signals, have received sparse investigation by considering …
lifex-fiber: an open tool for myofibers generation in cardiac computational models
Background Modeling the whole cardiac function involves the solution of several complex
multi-physics and multi-scale models that are highly computationally demanding, which call …
multi-physics and multi-scale models that are highly computationally demanding, which call …
lifex-ep: a robust and efficient software for cardiac electrophysiology simulations
Background Simulating the cardiac function requires the numerical solution of multi-physics
and multi-scale mathematical models. This underscores the need for streamlined, accurate …
and multi-scale mathematical models. This underscores the need for streamlined, accurate …