The lactoferrin phenomenon—a miracle molecule

P Kowalczyk, K Kaczyńska, P Kleczkowska… - Molecules, 2022 - mdpi.com
Numerous harmful factors that affect the human body from birth to old age cause many
disturbances, eg, in the structure of the genome, inducing cell apoptosis and their …

Lactoferrin, a multi-functional glycoprotein: Active therapeutic, drug nanocarrier & targeting ligand

AO Elzoghby, MA Abdelmoneem, IA Hassanin… - Biomaterials, 2020 - Elsevier
Recent progress in protein-based nanomedicine, inspired by the success of Abraxane®
albumin-paclitaxel nanoparticles, have resulted in novel therapeutics used for treatment of …

The evolving landscape of exosomes in neurodegenerative diseases: exosomes characteristics and a promising role in early diagnosis

S Rastogi, V Sharma, PS Bharti, K Rani… - International journal of …, 2021 - mdpi.com
Neurodegenerative diseases (ND) remains to be one of the biggest burdens on healthcare
systems and serves as a leading cause of disability and death. Alzheimer's disease (AD) is …

Disease-induced changes in salivary gland function and the composition of saliva

GB Proctor, AM Shaalan - Journal of dental research, 2021 - journals.sagepub.com
Although the physiological control of salivary secretion has been well studied, the impact of
disease on salivary gland function and how this changes the composition and function of …

Lactoferrin and its detection methods: A review

Y Zhang, C Lu, J Zhang - Nutrients, 2021 - mdpi.com
Lactoferrin (LF) is one of the major functional proteins in maintaining human health due to its
antioxidant, antibacterial, antiviral, and anti-inflammatory activities. Abnormal levels of LF in …

Biomarkers for Alzheimer's disease in the current state: a narrative review

S Gunes, Y Aizawa, T Sugashi, M Sugimoto… - International journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) has become a problem, owing to its high prevalence in an aging
society with no treatment available after onset. However, early diagnosis is essential for …

Prospective biomarkers of Alzheimer's disease: A systematic review and meta-analysis

RX Li, YH Ma, L Tan, JT Yu - Ageing Research Reviews, 2022 - Elsevier
Objective Alzheimer's disease (AD) involves a series of pathological changes and some
biomarkers were reported to assist in monitoring and predicting disease progression before …

Fluid biomarkers in frontotemporal dementia: past, present and future

IJ Swift, A Sogorb-Esteve, C Heller… - Journal of Neurology …, 2021 - jnnp.bmj.com
The frontotemporal dementia (FTD) spectrum of neurodegenerative disorders includes a
heterogeneous group of conditions. However, following on from a series of important …

Saliva–a new opportunity for fluid biopsy

Z Huang, X Yang, Y Huang, Z Tang, Y Chen… - Clinical Chemistry and …, 2023 - degruyter.com
Saliva is a complex biological fluid with a variety of biomolecules, such as DNA, RNA,
proteins, metabolites and microbiota, which can be used for the screening and diagnosis of …

Lactoferrin as a Human Genome “Guardian”—An Overall Point of View

I Bukowska-Ośko, D Sulejczak, K Kaczyńska… - International Journal of …, 2022 - mdpi.com
Structural abnormalities causing DNA modifications of the ethene and propanoadducts can
lead to mutations and permanent damage to human genetic material. Such changes may …