Sudden cardiac death in neuromuscular disorders

J Finsterer, C Stöllberger, C Maeztu - International journal of cardiology, 2016 - Elsevier
Objectives The heart is frequently affected in neuromuscular disorders (NMDs). Some of
these patients even experience sudden cardiac death (SCD). In the following review, we …

Low‐level tragus stimulation modulates atrial alternans and fibrillation burden in patients with paroxysmal atrial fibrillation

K Kulkarni, JP Singh, KA Parks… - Journal of the …, 2021 - Am Heart Assoc
Background Low‐level tragus stimulation (LLTS) has been shown to significantly reduce
atrial fibrillation (AF) burden in patients with paroxysmal AF. P‐wave alternans (PWA) is …

Cardiac contractility modulation in patients with heart failure—A review of the literature

G Bazoukis, A Saplaouras, P Efthymiou… - Heart Failure …, 2024 - Springer
Experimental in vivo and in vitro studies showed that electric currents applied during the
absolute refractory period can modulate cardiac contractility. In preclinical studies, cardiac …

Utility of a smartphone based system (cvrPhone) to predict short-term arrhythmia susceptibility

K Sohn, SP Dalvin, FM Merchant, K Kulkarni, F Sana… - Scientific reports, 2019 - nature.com
Repolarization alternans (RA) has been implicated in the pathogenesis of ventricular
arrhythmias and sudden cardiac death. We developed a 12-lead, blue-tooth/Smart-Phone …

Microvolt t-wave alternans is modulated by acute low-level tragus stimulation in patients with ischemic cardiomyopathy and heart failure

K Kulkarni, S Stavrakis, K Elkholey, JP Singh… - Frontiers in …, 2021 - frontiersin.org
Aims: Microvolt T-wave alternans (TWA), an oscillation in T-wave morphology of the
electrocardiogram (ECG), has been associated with increased susceptibility to ventricular …

Real-time closed-loop suppression of repolarization alternans reduces arrhythmia susceptibility in vivo

FM Merchant, O Sayadi, K Sohn, EH Weiss… - Circulation …, 2020 - Am Heart Assoc
Background: Repolarization alternans (RA) has been implicated in the pathogenesis of
ventricular arrhythmias and sudden cardiac death. Methods: We have developed a real …

Clinical potential of beat‐to‐beat diastolic interval control in preventing cardiac arrhythmias

K Kulkarni, RD Walton, AA Armoundas… - Journal of the …, 2021 - Am Heart Assoc
Life‐threatening ventricular arrhythmias and sudden cardiac death are often preceded by
cardiac alternans, a beat‐to‐beat oscillation in the T‐wave morphology or duration …

High-throughput phenotyping of human induced pluripotent stem cell-derived cardiomyocytes and neurons using electric field stimulation and high-speed …

NJ Daily, ZW Du, T Wakatsuki - Assay and drug development …, 2017 - liebertpub.com
Electrophysiology of excitable cells, including muscle cells and neurons, has been
measured by making direct contact with a single cell using a micropipette electrode. To …

Evolution of action potential alternans in rabbit heart during acute regional ischemia

I Martišienė, J Jurevičius, R Vosyliūtė… - BioMed research …, 2015 - Wiley Online Library
This study investigates the development of the spatiotemporal pattern of action potential
alternans during acute regional ischemia. Experiments were carried out in isolated …

State of the art on wearable and implantable devices for cardiac and respiratory monitoring

AA Armoundas, JP Singh, EK Heist… - … and Practical Implications, 2021 - Springer
Ambulatory monitoring devices are enabling a new paradigm of healthcare by continuously
collecting, processing, and interpreting long-term data aiming to provide reliable clinical …