Exploring animal models that resemble idiopathic pulmonary fibrosis

J Tashiro, GA Rubio, AH Limper, K Williams… - Frontiers in …, 2017 - frontiersin.org
Large multicenter clinical trials have led to two recently approved drugs for patients with
idiopathic pulmonary fibrosis (IPF); yet, both of these therapies only slow disease …

Animal models of fibrotic lung disease

B B. Moore, WE Lawson, TD Oury… - American journal of …, 2013 - atsjournals.org
Interstitial lung fibrosis can develop as a consequence of occupational or medical exposure,
as a result of genetic defects, and after trauma or acute lung injury leading to …

Inflammatory airway disease of horses—revised consensus statement

LL Couëtil, JM Cardwell, V Gerber… - Journal of veterinary …, 2016 - Wiley Online Library
The purpose of this manuscript is to revise and update the previous consensus statement on
inflammatory airway disease (IAD) in horses. Since 2007, a large number of scientific …

An official American Thoracic Society workshop report: use of animal models for the preclinical assessment of potential therapies for pulmonary fibrosis

RG Jenkins, BB Moore, RC Chambers… - American journal of …, 2017 - atsjournals.org
Numerous compounds have shown efficacy in limiting development of pulmonary fibrosis
using animal models, yet few of these compounds have replicated these beneficial effects in …

Emerging concepts in the pathogenesis of lung fibrosis

WD Hardie, SW Glasser, JS Hagood - The American journal of pathology, 2009 - Elsevier
Fibrogenesis is an often-deadly process with increasing world-wide incidence and limited
therapeutic options. Pulmonary fibrogenesis involves remodeling of the distal airspace and …

Viral infection and aging as cofactors for the development of pulmonary fibrosis

PK Naik, BB Moore - Expert review of respiratory medicine, 2010 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is a disease of unknown origin and progression that
primarily affects older adults. Accumulating clinical and experimental evidence suggests that …

Equine Herpesviruses 14

J Slater - Equine Infectious Diseases E-Book: Equine Infectious …, 2013 - books.google.com
The equine herpesviruses (EHVs) are highly successful pathogens of all members of the
Equidae family worldwide. 1-4 Of the nine EHVs characterized thus far, five types (EHV-1 to …

Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): infection with Equine …

EFSA Panel on Animal Health and Welfare … - EFSA …, 2022 - Wiley Online Library
Equine Herpesvirus‐1 infection has been assessed according to the criteria of the Animal
Health Law (AHL), in particular criteria of: Article 7 on disease profile and impacts, Article 5 …

Studying human respiratory disease in animals–role of induced and naturally occurring models

K Williams, J Roman - The Journal of pathology, 2016 - Wiley Online Library
Respiratory disorders like asthma, emphysema, and pulmonary fibrosis affect millions of
Americans and many more worldwide. Despite advancements in medical research that have …

Equine gammaherpesviruses: pathogenesis, epidemiology and diagnosis

G Fortier, E Van Erck, S Pronost, P Lekeux, E Thiry - The Veterinary Journal, 2010 - Elsevier
Equine gammaherpesviruses (γEHV) have been widely studied over the past 45years and
many isolates have been characterised. Despite this, the diagnosis of γEHV infection …