Hemorrhagic shock

JW Cannon - New England Journal of Medicine, 2018 - Mass Medical Soc
Hemorrhagic Shock | New England Journal of Medicine Skip to main content Access provided
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[HTML][HTML] Resuscitation with blood products in patients with trauma-related haemorrhagic shock receiving prehospital care (RePHILL): a multicentre, open-label …

N Crombie, HA Doughty, JRB Bishop… - The Lancet …, 2022 - thelancet.com
Background Time to treatment matters in traumatic haemorrhage but the optimal prehospital
use of blood in major trauma remains uncertain. We investigated whether use of packed red …

Perioperative considerations in management of the severely bleeding coagulopathic patient

G Erdoes, D Faraoni, A Koster, ME Steiner… - …, 2023 - pubs.asahq.org
Inherited and acquired coagulopathy are frequently associated with major bleeding in
severe trauma, cardiac surgery with cardiopulmonary bypass, and postpartum hemorrhage …

The medical response to multisite terrorist attacks in Paris

M Hirsch, P Carli, R Nizard, B Riou, B Baroudjian… - The Lancet, 2015 - thelancet.com
Friday, Nov 13, 2015. It's 2130 h when the Assistance Publique-Hôpitaux de Paris (APHP) is
alerted to the explosions that have just occurred at the Stade de France, a stadium in Saint …

[HTML][HTML] Carbon nano-onion-mediated dual targeting of P-selectin and P-glycoprotein to overcome cancer drug resistance

H Wang, Y Liang, Y Yin, J Zhang, W Su… - Nature …, 2021 - nature.com
The transmembrane P-glycoprotein (P-gp) pumps that efflux drugs are a major mechanism
of cancer drug resistance. They are also important in protecting normal tissue cells from …

[HTML][HTML] Hemorrhagic shock drives glycocalyx, barrier and organ dysfunction early after polytrauma

R Halbgebauer, CK Braun, S Denk, B Mayer… - Journal of critical …, 2018 - Elsevier
Polytrauma (PT) is frequently associated with hemorrhagic shock (HS), which increases
morbidity and mortality. Although various aspects of HS have been addressed in PT …

Endotheliopathy of trauma is an on-scene phenomenon, and is associated with multiple organ dysfunction syndrome: a prospective observational study

DN Naumann, J Hazeldine, DJ Davies, J Bishop… - Shock, 2018 - journals.lww.com
Background: Trauma patients are vulnerable to coagulopathy and inflammatory dysfunction
associated with endotheliopathy of trauma (EoT). In vitro evidence has suggested that …

An international normalized ratio–based definition of acute traumatic coagulopathy is associated with mortality, venous thromboembolism, and multiple organ failure …

ID Peltan, LKV Vusse, RV Maier… - Critical care …, 2015 - journals.lww.com
Objectives: Acute traumatic coagulopathy is associated with adverse outcomes including
death. Previous studies examining acute traumatic coagulopathy's relation with mortality are …

The use of whole blood in US military operations in Iraq, Syria, and Afghanistan since the introduction of low‐titer Type O whole blood: feasibility, acceptability …

CK Vanderspurt, PC Spinella, AP Cap, R Hill… - …, 2019 - Wiley Online Library
BACKGROUND Hemorrhage is the leading cause of preventable death in military and
civilian traumatic injury. Blood product resuscitation improves survival. Low‐titer Type O …

Tactical damage control resuscitation

AD Fisher, EA Miles, AP Cap, G Strandenes… - Military …, 2015 - academic.oup.com
ABSTRACT Recently the Committee on Tactical Combat Casualty Care changed the
guidelines on fluid use in hemorrhagic shock. The current strategy for treating hemorrhagic …