Prefrontal cortex and depression
DA Pizzagalli, AC Roberts - Neuropsychopharmacology, 2022 - nature.com
The prefrontal cortex (PFC) has emerged as one of the regions most consistently impaired in
major depressive disorder (MDD). Although functional and structural PFC abnormalities …
major depressive disorder (MDD). Although functional and structural PFC abnormalities …
Reflecting on rumination: Consequences, causes, mechanisms and treatment of rumination
ER Watkins, H Roberts - Behaviour research and therapy, 2020 - Elsevier
We review research showing that rumination has multiple negative consequences:(a)
exacerbating psychopathology by magnifying and prolonging negative mood states …
exacerbating psychopathology by magnifying and prolonging negative mood states …
GABA-modulating bacteria of the human gut microbiota
The gut microbiota affects many important host functions, including the immune response
and the nervous system. However, while substantial progress has been made in growing …
and the nervous system. However, while substantial progress has been made in growing …
Resting-state connectivity biomarkers define neurophysiological subtypes of depression
Biomarkers have transformed modern medicine but remain largely elusive in psychiatry,
partly because there is a weak correspondence between diagnostic labels and their …
partly because there is a weak correspondence between diagnostic labels and their …
Psychedelics in psychiatry: neuroplastic, immunomodulatory, and neurotransmitter mechanisms
Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …
Rapid antidepressant effects of the psychedelic ayahuasca in treatment-resistant depression: a randomized placebo-controlled trial
F Palhano-Fontes, D Barreto, H Onias… - Psychological …, 2019 - cambridge.org
BackgroundRecent open-label trials show that psychedelics, such as ayahuasca, hold
promise as fast-onset antidepressants in treatment-resistant depression. MethodsTo test the …
promise as fast-onset antidepressants in treatment-resistant depression. MethodsTo test the …
Emotion and the prefrontal cortex: An integrative review.
The prefrontal cortex (PFC) plays a critical role in the generation and regulation of emotion.
However, we lack an integrative framework for understanding how different emotion-related …
However, we lack an integrative framework for understanding how different emotion-related …
Statistical harmonization corrects site effects in functional connectivity measurements from multi‐site fMRI data
Acquiring resting‐state functional magnetic resonance imaging (fMRI) datasets at multiple
MRI scanners and clinical sites can improve statistical power and generalizability of results …
MRI scanners and clinical sites can improve statistical power and generalizability of results …
Mindfulness-based treatments for posttraumatic stress disorder: a review of the treatment literature and neurobiological evidence
Mindfulness-based treatments for posttraumatic stress disorder (PTSD) have emerged as
promising adjunctive or alternative intervention approaches. A scoping review of the …
promising adjunctive or alternative intervention approaches. A scoping review of the …
Sensation and psychiatry: linking age-related hearing loss to late-life depression and cognitive decline
BR Rutherford, K Brewster, JS Golub… - American Journal of …, 2018 - Am Psychiatric Assoc
Recent research has linked age-related hearing loss to impaired performance across
cognitive domains and increased risk for dementia diagnosis. The data linking hearing …
cognitive domains and increased risk for dementia diagnosis. The data linking hearing …