Exposure of biological cells to high-voltage, short-duration electric pulses causes a transient
increase in their plasma membrane permeability, allowing transmembrane transport of …

Irreversible electroporation can be used as a nonthermal energy source to ablate tissue.
Cardiac catheter ablation by irreversible electroporation may be a safe and effective …

Objectives: The authors report the first acute clinical experience of atrial fibrillation ablation
with PEF—both epicardial box lesions during cardiac surgery, and catheter-based PV …

Background Radiofrequency (RF) has become an accepted energy source for myocardial
ablation but may result in discontinuous lesions and nontargeted tissue injury. We examined …

Introduction Irreversible electroporation (IRE) utilizing high voltage pulses is an emerging
strategy for catheter-based cardiac ablation with considerable growth in the preclinical …

It was recently suggested that applying high-frequency short biphasic pulses (HF-IRE)
reduces pain and muscle contractions in electrochemotherapy and irreversible ablation …

Introduction Pulsed field ablation (PFA) exploits the delivery of short high-voltage shocks to
induce cells death via irreversible electroporation. The therapy offers a potential paradigm …

Background Esophageal ulceration and fistula are severe complications of pulmonary vein
isolation using thermal ablation. Nonthermal irreversible electroporation (NTIRE) is a …

Electroporation is employed ever more frequently and broadly to deliver energy to tissues
and liquid media in various applications, thus answering questions on the associated …

Targeted cellular ablation is being increasingly used in the treatment of arrhythmias and
structural heart disease. Catheter-based ablation for atrial fibrillation (AF) is considered a …