Recent progress in the understanding of autoimmune adrenal disease, including a detailed
analysis of a group of patients with Addison's disease (AD), has been reviewed. Criteria for …

Autoimmune Polyendocrine Syndromes (APS) were initially defined as a multiple endocrine
gland insufficiency associated to an autoimmune disease in a patient. Neufeld & Blizzard …

The American Academy of Allergy, Asthma & Immunology (AAAAI) and the American
College of Allergy, Asthma & Immunology (ACAAI) have jointly accepted responsibility for …

The purpose of this Practice Parameter for the Diagnosis and Management of Primary
Immunodeficiency is to provide the consultant allergist/immunologist with a practical guide …

Autoimmune diseases affect 5% to 8% of the population, and females are more susceptible
to these diseases than males. Here, we analyzed human thymic transcriptome and revealed …

Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy is a rare autosomal
recessive disorder characterized by hypoparathyroidism, adrenal failure, chronic …

Type I (insulin-dependent) diabetes mellitus is a heterogeneous disease with major
subdivisions termed Type 1A (immune-mediated) and Type 1B. Immune-mediated diabetes …

The autoimmune regulator (AIRE) protein is a putative transcription regulator with two plant
homeodomain-type zinc fingers, a putative DNA-binding domain (SAND), and four nuclear …

The plant homeodomain (PHD) finger is found in many chromatin-remodeling proteins. This
small~ 65-residue domain functions as an “effector” that binds specific epigenetic marks on …

The autoimmune regulator (AIRE) is a gene where mutations cause the recessively inherited
disorder called autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy …