[HTML][HTML] Cancer hallmarks intersect with neuroscience in the tumor microenvironment

D Hanahan, M Monje - Cancer cell, 2023 - cell.com
The mechanisms underlying the multistep process of tumorigenesis can be distilled into a
logical framework involving the acquisition of functional capabilities, the so-called hallmarks …

Augustus Waller's foresight realized: SARM1 in peripheral neuropathies

S Geisler - Current Opinion in Neurobiology, 2024 - Elsevier
Peripheral neuropathy is a common neurodegenerative condition characterized by
numbness, tingling, pain, and weakness that frequently starts in the distal limbs. Arising from …

Crosstalk between small-cell lung cancer cells and astrocytes mimics brain development to promote brain metastasis

F Qu, SC Brough, W Michno, CJ Madubata… - Nature Cell …, 2023 - nature.com
Brain metastases represent an important clinical problem for patients with small-cell lung
cancer (SCLC). However, the mechanisms underlying SCLC growth in the brain remain …

Targeting the peripheral neural-tumour microenvironment for cancer therapy

D Yaniv, B Mattson, S Talbot, FO Gleber-Netto… - Nature Reviews Drug …, 2024 - nature.com
As the field of cancer neuroscience expands, the strategic targeting of interactions between
neurons, cancer cells and other elements in the tumour microenvironment represents a …

Neuroscience and oncology: state-of-the-art and new perspectives

F Winkler - Current opinion in neurology, 2023 - journals.lww.com
Neuro-cancer interactions are manyfold, have multiple clinical implications, and can lead to
novel neuroscience-instructed cancer therapies and improved therapies of neurological …

Nervous system contributions to small cell lung cancer: Lessons from diverse oncological studies

S Liao, K Kang, Z Yao, Y Lu - Biochimica et Biophysica Acta (BBA)-Reviews …, 2024 - Elsevier
The nervous system plays a vital role throughout the entire lifecycle and it may regulate the
formation, development and metastasis of tumors. Small cell lung cancer is a typical …

Intrinsic and Microenvironmental Drivers of Glioblastoma Invasion

E De Fazio, M Pittarello, A Gans, B Ghosh… - International journal of …, 2024 - mdpi.com
Gliomas are diffusely infiltrating brain tumors whose prognosis is strongly influenced by their
extent of invasion into the surrounding brain tissue. While lower-grade gliomas present more …

Precise timing of audiovisual stimulation conquers chemobrain

LC Mehl, EM Gibson - Trends in Cancer, 2024 - cell.com
In a recent study, Kim et al. utilized gamma entrainment using sensory stimuli (GENUS) to
rescue cognitive impairment and glial dysregulation associated with cisplatin and …

Neuromodulation as an anticancer strategy

A Kumaria, K Ashkan - Cancer Medicine, 2023 - Wiley Online Library
Neuromodulation as an anticancer strategy - Kumaria - 2023 - Cancer Medicine - Wiley Online
Library Skip to Article Content Skip to Article Information Wiley Online Library Wiley Online …

Direct excitatory synapses between neurons and tumor cells drive brain metastatic seeding of breast cancer and melanoma

V Venkataramani, MA Karreman, LC Nguyen… - bioRxiv, 2024 - biorxiv.org
Interactions between neurons and cancer cells are found in many malignancies, but their
relevance for metastatic organ colonization remain largely unknown. It is also unclear …