Multidrug resistance (MDR) presents a serious challenge to the efficiency of cancer
treatment, and may be associated with the overexpression of drug efflux pumps. P …

Chemotherapy is one of the main methods for cancer treatment. However, despite many
advances in the design of anticancer drugs, their efficiency is limited due to their high toxicity …

The introduction of imatinib (IM), a BCR-ABL1 tyrosine kinase inhibitor (TKI), has
represented a significant advance in the first-line treatment of chronic myeloid leukemia …

This work aimed at preparing nanomicelles from N-benzyl-N, O-succinyl chitosan (NBSCh)
loaded with a curcumin analog, 2, 6-bis ((3-methoxy-4-hydroxyphenyl) methylene) …

The pharmacological propensities of curcumin have been reported in a plethora of pre-
clinical and clinical studies. However, innate attributes account for extremely low oral …

Nano-micelles are self-assembling colloidal dispersions applied to enhance the anticancer
efficacy of chemotherapeutic agents. In this study, the conjugate of quarternized chitosan …

Acute myeloid leukemia (AML) remains an insidious neoplasm due to the percentage of
patients who develop resistance to both classic chemotherapy and emerging drugs …

Combining phytochemicals with chemotherapeutic drugs has demonstrated the potential to
surmount drug resistance. In this paper, we explore the efficacy of pentagalloyl glucose …

The development of multidrug resistance (MDR) has seriously impeded the efficacy of drug
treatment of chronic myeloid leukemia (CML). Recent studies have indicated that S100 …

Papillary renal cell carcinoma (pRCC) is one of the epithelial renal cell carcinoma (RCC)
histological subtypes. Ferroptosis is a new iron-dependent form of cell death that has been …