A literature review of traumatic brain injury biomarkers
Research into TBI biomarkers has accelerated rapidly in the past decade owing to the
heterogeneous nature of TBI pathologies and management, which pose challenges to TBI …
heterogeneous nature of TBI pathologies and management, which pose challenges to TBI …
The role of microRNAs in neurodegenerative diseases: a review
S Li, Z Lei, T Sun - Cell Biology and Toxicology, 2023 - Springer
MicroRNAs (miRNAs) are non-coding RNAs which are essential post-transcriptional gene
regulators in various neuronal degenerative diseases and playact a key role in these …
regulators in various neuronal degenerative diseases and playact a key role in these …
Natural RNA circles function as efficient microRNA sponges
TB Hansen, TI Jensen, BH Clausen, JB Bramsen… - Nature, 2013 - nature.com
MicroRNAs (miRNAs) are important post-transcriptional regulators of gene expression that
act by direct base pairing to target sites within untranslated regions of messenger RNAs …
act by direct base pairing to target sites within untranslated regions of messenger RNAs …
MicroRNA-mediated inhibition of transgene expression reduces dorsal root ganglion toxicity by AAV vectors in primates
J Hordeaux, EL Buza, B Jeffrey, C Song… - Science translational …, 2020 - science.org
Delivering adeno-associated virus (AAV) vectors into the central nervous system of
nonhuman primates (NHPs) via the blood or cerebral spinal fluid is associated with dorsal …
nonhuman primates (NHPs) via the blood or cerebral spinal fluid is associated with dorsal …
MiR-133b promotes neural plasticity and functional recovery after treatment of stroke with multipotent mesenchymal stromal cells in rats via transfer of exosome …
To test, in vivo, the hypothesis that exosomes from multipotent mesenchymal stromal cells
(MSCs) mediate microRNA 133b (miR-133b) transfer which promotes neurological recovery …
(MSCs) mediate microRNA 133b (miR-133b) transfer which promotes neurological recovery …
Targeting noncoding RNAs in disease
BD Adams, C Parsons, L Walker… - The Journal of …, 2017 - Am Soc Clin Investig
Many RNA species have been identified as important players in the development of chronic
diseases, including cancer. Over the past decade, numerous studies have highlighted how …
diseases, including cancer. Over the past decade, numerous studies have highlighted how …
Exosomes/miRNAs as mediating cell-based therapy of stroke
Cell-based therapy, eg, multipotent mesenchymal stromal cell (MSC) treatment, shows
promise for the treatment of various diseases. The strong paracrine capacity of these cells …
promise for the treatment of various diseases. The strong paracrine capacity of these cells …
Repression of α-synuclein expression and toxicity by microRNA-7
E Junn, KW Lee, BS Jeong, TW Chan… - Proceedings of the …, 2009 - National Acad Sciences
α-Synuclein is a key protein in Parkinson's disease (PD) because it accumulates as fibrillar
aggregates in pathologic hallmark features in affected brain regions, most notably in nigral …
aggregates in pathologic hallmark features in affected brain regions, most notably in nigral …
Neuronal exosomal miRNA-dependent translational regulation of astroglial glutamate transporter GLT1
L Morel, M Regan, H Higashimori, SK Ng… - Journal of Biological …, 2013 - ASBMB
Perisynaptic astrocytes express important glutamate transporters, especially excitatory
amino acid transporter 2 (EAAT2, rodent analog GLT1) to regulate extracellular glutamate …
amino acid transporter 2 (EAAT2, rodent analog GLT1) to regulate extracellular glutamate …
MicroRNA-21 is up-regulated in allergic airway inflammation and regulates IL-12p35 expression
Allergic airway inflammation is characterized by marked in situ changes in gene and protein
expression, yet the role of microRNAs (miRNAs), a new family of key mRNA regulatory …
expression, yet the role of microRNAs (miRNAs), a new family of key mRNA regulatory …