Modulating the tachykinin: Role of substance P and neurokinin receptor expression in ocular surface disorders
Substance P (SP) is a tachykinin expressed by various cells in the nervous and immune
systems. SP is predominantly released by neurons and exerts its biological and …
systems. SP is predominantly released by neurons and exerts its biological and …
Neuropeptides and their receptors: innovative science providing novel therapeutic targets
SD Brain, HM Cox - British journal of pharmacology, 2006 - Wiley Online Library
This review examines our current understanding of the roles of some of the best known
neuropeptides that have played major roles in our combined research programmes …
neuropeptides that have played major roles in our combined research programmes …
Gait analysis and pain response of two rodent models of osteoarthritis
The purpose of this study was to compare the gait parameters recorded on the CatWalk and
the mechanical sensitivity with von Frey filaments of two putative models of osteoarthritis …
the mechanical sensitivity with von Frey filaments of two putative models of osteoarthritis …
Involvement of transient receptor potential vanilloid 1 in the vascular and hyperalgesic components of joint inflammation
Objective To investigate the endogenous involvement of transient receptor potential
vanilloid 1 (TRPV1) in a model of knee joint inflammation in the mouse. Methods Following …
vanilloid 1 (TRPV1) in a model of knee joint inflammation in the mouse. Methods Following …
[HTML][HTML] Restoration of regulatory T-cell function in dry eye disease by antagonizing substance P/Neurokinin-1 receptor
Y Taketani, A Marmalidou, TH Dohlman… - The American Journal of …, 2020 - Elsevier
Substance P (SP) is a tachykinin neuropeptide, implicated in the pathogenesis of various
inflammatory conditions and a critical mediator in pain transmission. Recently, the role of SP …
inflammatory conditions and a critical mediator in pain transmission. Recently, the role of SP …
Substance P at the nexus of mind and body in chronic inflammation and affective disorders.
MA Rosenkranz - Psychological bulletin, 2007 - psycnet.apa.org
For decades, research has demonstrated that chronic diseases characterized by
dysregulation of inflammation are particularly susceptible to exacerbation by stress and …
dysregulation of inflammation are particularly susceptible to exacerbation by stress and …
Crosstalk between epithelial cells, neurons and immune mediators in HSV-1 skin infection
Herpes simplex virus type 1 (HSV-1) infection is highly prevalent in humans, with
approximately two-thirds of the world population living with this virus. However, only a …
approximately two-thirds of the world population living with this virus. However, only a …
Hypoalgesic and motor effects of kaltenborn mobilization on elderly patients with secondary thumb carpometacarpal osteoarthritis: a randomized controlled trial
JH Villafañe, GB Silva, SA Diaz-Parreño… - Journal of manipulative …, 2011 - Elsevier
OBJECTIVE: This study evaluated the effects of Kaltenborn manual therapy on sensory and
motor function in elderly patients with secondary carpometacarpal osteoarthritis (CMC OA) …
motor function in elderly patients with secondary carpometacarpal osteoarthritis (CMC OA) …
[HTML][HTML] Neurokinin receptors and their implications in various autoimmune diseases
Neurokinin receptors belong to the GPCRs family and are ubiquitously expressed
throughout the nervous and immune systems. Neurokinin receptors in coordination with …
throughout the nervous and immune systems. Neurokinin receptors in coordination with …
Substance P and chronic pain in patients with chronic inflammation of connective tissue
Objective Evidence suggests that substance P (SP) is involved in chronic joint inflammation,
such as the pathogenesis of rheumatoid arthritis and osteoarthritis. The goal of the research …
such as the pathogenesis of rheumatoid arthritis and osteoarthritis. The goal of the research …