Emerging role of non-coding RNAs in neuroinflammation mediated by microglia and astrocytes

R Yang, B Yang, W Liu, C Tan, H Chen… - Journal of …, 2023 - Springer
Neuroinflammation has been implicated in the initiation and progression of several central
nervous system (CNS) disorders, including Alzheimer's disease, Parkinson's disease …

Block and lock HIV cure strategies to control the latent reservoir

CL Ahlenstiel, G Symonds, SJ Kent… - Frontiers in cellular and …, 2020 - frontiersin.org
The HIV latent reservoir represents the major challenge to cure development. Residing in
resting CD4+ T cells and myeloid cells at multiple locations in the body, including sanctuary …

LncRNA TMPO-AS1 promotes esophageal squamous cell carcinoma progression by forming biomolecular condensates with FUS and p300 to regulate TMPO …

XJ Luo, MM He, J Liu, JB Zheng, QN Wu… - … & molecular medicine, 2022 - nature.com
Esophageal squamous cell carcinoma (ESCC) is one of the most life-and health-threatening
malignant diseases worldwide, especially in China. Long noncoding RNAs (lncRNAs) have …

Examples of inverse comorbidity between cancer and neurodegenerative diseases: a possible role for noncoding RNA

M Salemi, MP Mogavero, G Lanza, LM Mongioì… - Cells, 2022 - mdpi.com
Cancer is one of the most common causes of death; in parallel, the incidence and
prevalence of central nervous system diseases are equally high. Among neurodegenerative …

LncRNAs and CircRNAs in cancer

X Yin, H Lin, L Lin, L Miao, J He, Z Zhuo - MedComm, 2022 - Wiley Online Library
It is well known that noncoding RNAs (ncRNAs) cannot encode proteins, but they can play
important regulatory roles in tumors by combining with proteins, RNAs, and DNAs. As more …

HIV UTR, LTR, and epigenetic immunity

J Zhang, C Crumpacker - Viruses, 2022 - mdpi.com
The duel between humans and viruses is unending. In this review, we examine the HIV RNA
in the form of un-translated terminal region (UTR), the viral DNA in the form of long terminal …

[HTML][HTML] Long non-coding RNAs and immune cells: Unveiling the role in viral infections

D Zhang, M Zhang, L Zhang, W Wang, S Hua… - Biomedicine & …, 2024 - Elsevier
Viral infections present significant challenges to human health, underscoring the importance
of understanding the immune response for effective therapeutic strategies. Immune cell …

Aid or antagonize: nuclear long noncoding RNAs regulate host responses and outcomes of viral infections

V Kulkarni, S Jayakumar, M Mohan, S Kulkarni - Cells, 2023 - mdpi.com
Long noncoding RNAs (lncRNAs) are transcripts measuring> 200 bp in length and devoid of
protein-coding potential. LncRNAs exceed the number of protein-coding mRNAs and …

Fused in liposarcoma protein, a new player in the regulation of HIV-1 transcription, binds to known and newly identified LTR G-quadruplexes

E Ruggiero, I Frasson, E Tosoni… - ACS infectious …, 2022 - ACS Publications
HIV-1 integrated long terminal repeat (LTR) promoter activity is modulated by folding of its G-
rich region into non-canonical nucleic acids structures, such as G-quadruplexes (G4s), and …

LncRNAs in the type I interferon antiviral response

B Suarez, L Prats-Mari, JP Unfried, P Fortes - International Journal of …, 2020 - mdpi.com
The proper functioning of the immune system requires a robust control over a delicate
equilibrium between an ineffective response and immune overactivation. Poor responses to …