Background Amitriptyline is a tricyclic antidepressant that is widely used to treat chronic
neuropathic pain (pain due to nerve damage) and fibromyalgia, and is recommended in …

Persistent pain disorders are usually not adequately alleviated by nonsteroidal anti‐
inflammatory drugs or other simple analgesics. Use of antidepressants as adjuvant therapy …

Context Fibromyalgia syndrome (FMS) is a chronic pain disorder associated with multiple
debilitating symptoms and high disease-related costs. Effective treatment options are …

Introduction: Fibromyalgia is a syndrome characterized by chronic generalized pain in
addition to different symptoms such as fatigue, sleep disturbances, stiffness, cognitive …

Background Fibromyalgia is a clinically well‐defined chronic condition with a
biopsychosocial aetiology. Fibromyalgia is characterized by chronic widespread …

Objective To systematically review the efficacy of treatment of fibromyalgia syndrome (FMS)
with antidepressants. Methods We screened Medline, PsychINFO, SCOPUS, and the …

Fibromyalgia is characterized by chronic generalized pain accompanied by a wide range of
clinical manifestations. Most clinical practice guidelines recommend multidisciplinary …

OBJECTIVES: To review the literature on pharmacological treatments for fibromyalgia.
METHODS: Relative efficacy was estimated in terms of outcome measures highlighted by …

Background This is an updated version of the original Cochrane review published in Issue
12, 2012. That review considered both fibromyalgia and neuropathic pain, but the efficacy of …

The aim of this study was to review the evidence supporting the use of anti-depressants in
painful rheumatological conditions. A systematic review of papers published between 1966 …