[HTML][HTML] Bone fracture healing in mechanobiological modeling: A review of principles and methods
Bone fracture is a very common body injury. The healing process is physiologically complex,
involving both biological and mechanical aspects. Following a fracture, cell migration …
involving both biological and mechanical aspects. Following a fracture, cell migration …
Treatment of critical-sized bone defects: clinical and tissue engineering perspectives
E Roddy, MR DeBaun, A Daoud-Gray, YP Yang… - European Journal of …, 2018 - Springer
Critical-sized bone defects are defined as those that will not heal spontaneously within a
patient's lifetime. Current treatment options include vascularized bone grafts, distraction …
patient's lifetime. Current treatment options include vascularized bone grafts, distraction …
Industry sponsorship and research outcome
Background Clinical research affecting how doctors practice medicine is increasingly
sponsored by companies that make drugs and medical devices. Previous systematic …
sponsored by companies that make drugs and medical devices. Previous systematic …
[HTML][HTML] TGF-β and BMP signaling in osteoblast differentiation and bone formation
Transforming growth factor-beta (TGF-β)/bone morphogenic protein (BMP) signaling is
involved in a vast majority of cellular processes and is fundamentally important throughout …
involved in a vast majority of cellular processes and is fundamentally important throughout …
[HTML][HTML] Bone fracture healing: cell therapy in delayed unions and nonunions
E Gómez-Barrena, P Rosset, D Lozano, J Stanovici… - Bone, 2015 - Elsevier
Bone fracture healing impairment related to mechanical problems has been largely
corrected by advances in fracture management. Better protocols, more strict controls of time …
corrected by advances in fracture management. Better protocols, more strict controls of time …
Diaphyseal long bone nonunions—types, aetiology, economics, and treatment recommendations
M Rupp, C Biehl, M Budak, U Thormann… - International …, 2018 - Springer
The intention of the current article is to review the epidemiology with related socioeconomic
costs, pathophysiology, and treatment options for diaphyseal long bone delayed unions and …
costs, pathophysiology, and treatment options for diaphyseal long bone delayed unions and …
Extracellular signaling molecules to promote fracture healing and bone regeneration
KD Hankenson, K Gagne, M Shaughnessy - Advanced drug delivery …, 2015 - Elsevier
To date, the delivery of signaling molecules for bone regeneration has focused primarily on
factors that directly affect the bone formation pathways (osteoinduction) or that serve to …
factors that directly affect the bone formation pathways (osteoinduction) or that serve to …
Bone morphogenetic proteins: facts, challenges, and future perspectives
AC Carreira, FH Lojudice, E Halcsik… - Journal of dental …, 2014 - journals.sagepub.com
Bone morphogenetic proteins (BMPs) are members of the TGF-β superfamily, acting as
potent regulators during embryogenesis and bone and cartilage formation and repair. Cell …
potent regulators during embryogenesis and bone and cartilage formation and repair. Cell …
[HTML][HTML] Enhanced bone regeneration via spatiotemporal and controlled delivery of a genetically engineered BMP-2 in a composite Hydrogel
X Chen, B Tan, Z Bao, S Wang, R Tang, Z Wang… - Biomaterials, 2021 - Elsevier
Scaffolds functionalized with bone morphogenetic protein-2 (BMP-2) have shown great
potential for bone regeneration. However, structural instability and the necessity for supra …
potential for bone regeneration. However, structural instability and the necessity for supra …
Personalized immunotherapy against several neuronal and brain tumors
S Kuttruff-coqui, T Weinschenk, J Fritsche… - US Patent …, 2021 - Google Patents
2014-11-12 Assigned to IMMATICS BIOTECHNOLOGIES GMBH reassignment IMMATICS
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …