[HTML][HTML] Emerging translational strategies and challenges for enhancing regulatory T cell therapy for graft-versus-host disease

KL Hippen, M Hefazi, JH Larson, BR Blazar - Frontiers in immunology, 2022 - frontiersin.org
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative therapy for
many types of cancer. Genetic disparities between donor and host can result in immune …

Embryonic stem cell-derived exosomes inhibit doxorubicin-induced TLR4-NLRP3-mediated cell death-pyroptosis

Z Tavakoli Dargani, DK Singla - American Journal of …, 2019 - journals.physiology.org
Doxorubicin (Dox)-induced cardiac side effects are regulated through increased oxidative
stress and apoptosis. However, it remains unknown whether Dox induces the specific …

Interactions of mesenchymal stromal/stem cells and immune cells following MSC-based therapeutic approaches in rheumatoid arthritis

S Dehnavi, M Sadeghi, JT Afshari, M Mohammadi - Cellular Immunology, 2023 - Elsevier
Rheumatoid arthritis (RA) is considered to be a degenerative and progressive autoimmune
disorder. Although several medicinal regimens are used to treat RA, potential adverse …

[HTML][HTML] Comparative transcriptomic analysis of subcutaneous adipose tissue from local pig breeds

A Albuquerque, C Óvilo, Y Núñez, R Benítez… - Genes, 2020 - mdpi.com
When compared to modern lean-type breeds, Portuguese local Alentejano (AL) and Bísaro
(BI) pig breeds present a high potential for subcutaneous and intramuscular fat (IMF) …

[HTML][HTML] Mogroside IIE Inhibits Digestive Enzymes via Suppression of Interleukin 9/Interleukin 9 Receptor Signalling in Acute Pancreatitis

J Xiao, K Huang, H Lin, Z Xia, J Zhang, D Li… - Frontiers in …, 2020 - frontiersin.org
The incidence of pancreatitis (AP) is increasing and there is no specific treatment available.
Intracellular digestive enzyme activation is a key event in the pathogenesis of AP …

[HTML][HTML] Bone marrow regulatory T cells are a unique population, supported by niche-specific cytokines and plasmacytoid dendritic cells, and required for chronic graft …

J Nicholls, B Cao, L Le Texier, LY Xiong… - Frontiers in Cell and …, 2021 - frontiersin.org
Regulatory T cell (Treg) reconstitution is essential for reestablishing tolerance and
maintaining homeostasis following stem-cell transplantation. We previously reported that …

Bone marrow mesenchymal stem cells suppress IL-9 in adjuvant-induced arthritis

SS Abd-Elhalem, NZ Haggag, NA El-Shinnawy - Autoimmunity, 2018 - Taylor & Francis
Abstract Interleukin-9 (IL-9) has been shown to be upregulated in rheumatoid arthritis (RA).
The exact role of IL-9 has not yet been effectively studied. Mesenchymal stem cells (MSCs) …

Group 2 innate lymphoid cells (ILC2s): The spotlight in asthma pathogenesis and lung tissue injury

S Sadik, Y Lu, S Zhu, J Cai, LL Mi - Allergologia et Immunopathologia, 2021 - all-imm.com
Asthma is a heterogeneous disease with ranging etiology and severity. Asthma is a disease
of chronic inflammation of the airways, with clinical symptoms of wheezing, breathlessness …

[HTML][HTML] The critical role of interleukin-6 in protection against neurotropic flavivirus infection

TT Auroni, K Arora, JP Natekar, H Pathak… - Frontiers in Cellular …, 2023 - frontiersin.org
West Nile virus (WNV) and Japanese encephalitis virus (JEV) are emerging mosquito-borne
flaviviruses causing encephalitis globally. No specific drug or therapy exists to treat flavivirus …

[HTML][HTML] The Role of IL-9 Polymorphisms and Serum IL-9 Levels in Carcinogenesis and Survival Rate for Laryngeal Squamous Cell Carcinoma

A Pasvenskaite, R Liutkeviciene, G Gedvilaite… - Cells, 2021 - mdpi.com
Recent studies have described the dichotomous function of IL-9 in various cancer diseases.
However, its function has still not been analysed in laryngeal squamous cell carcinoma …