Multiple studies around the world suggest that syphilis is re-emerging. Ocular syphilis–with a
wide range of presentations, most of which are subtypes of uveitis–has become an …

Regulated cell death contributes to a variety of physiological and pathological events and is
essential for maintaining physiological equilibrium. Specifically triggering programmed cell …

Small cell lung cancer (SCLC) is one of the most devastating type of human lung cancer and
has a high propensity to metastasize into the brain. Cuproptosis recently has been defined …

Comprehensive proteome-wide analysis of the syphilis spirochete, Treponema pallidum
ssp. pallidum, is technically challenging due to high sample complexity, difficulties with …

Syphilis continues to be a significant public health concern worldwide. The disease is
endemic in many low-and middle-income countries, and rates have risen sharply in high …

Treponema pallidum subspecies pallidum, the causative agent of syphilis, traverses the
vascular endothelium to gain access to underlying tissue sites. Herein, we investigate the …

The major human spirochetal pathogens (Leptospira, Borrelia, and Treponema) are difficult
to diagnose and lack vaccines to prevent infections. Infection by these spirochetes does not …

Treponema pallidum subsp. pallidum is the causative agent of syphilis, a human-specific
sexually transmitted infection that causes a multistage disease with diverse clinical …

The success in preventing hepatitis B virus and human papillomavirus infections by means
of vaccination paves the way for the development of other vaccines to prevent sexually …

Cancer represents a major threat to human health, being a primary cause of mortality from
diseases. The conventional methods for detection of tumor biomarker in clinical settings are …